HENGPHASATPORN Kowit

Affiliation
Center for Computational Sciences
Official title
Assistant Professor
ORCID
0000-0001-8501-3844
Email
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Research fields
Bio-related chemistry
Biomolecular chemistry
Molecular biology
Evolutionary biology
Research keywords
Drug discovery and design
Molecular Dynamics Simulation
Research projects
FMO/ML-Guided Drug Design: Accelerating Novel Inhibitor Development and Drug Discovery2024-04 -- 2027-03Kowit HengphasatpornThe Japan Society for the Promotion of Science (JSPS)/Kakenhi, WAKATE3,640,000Yen
Development of Novel Computational Methods for Ligand-Protein Complex Structure Exploration and Application in Drug Discovery.2024-04 -- 2025-03Kowit HengphasatpornToyota Riken Scholar/1,000,000Yen
Discovery of the antiviral inhibitors based on an in silico complex structure constructed by PaCS-MD/FMO technique.2022-04 -- 2025-03Kowit HengphasatpornTsukuba Basic Research Support Program (Type S)/3,000,000Yen
Career history
2022-04 -- (current)筑波大学計算科学研究センター助教
2019-09 -- 2022-03筑波大学計算科学研究センター研究員
Degree
2019Doctor of Philosophy (Ph.D.) in Bioinformatics and Computational BiologyChulalongkorn University
Academic societies
2022 -- (current)PROTEIN SCIENCE SOCIETY OF JAPAN
2022 -- (current)THE BIOPHYSICAL SOCIETY OF JAPAN
Articles
Conference, etc.
  • Unlocking Antiviral Insights: FMO, Docking, MD Illuminate Halogen Interactions in Drug Design
    HENGPHASATPORN Kowit
    8th Japan-Thai workshop on Theoretical and Computational Chemistry 2023/2024-01-19--2024-01-20
  • Insights into molecular metabolism of herbicide-resistant CYP81As through molecular docking and MM/GBSA analysis
    HENGPHASATPORN Kowit
    8th Edition of Global Congress on PLANT BIOLOGY AND BIOTECHNOLOGY2024-03-24/2024-03-24--2024-03-27
  • Combining Quantum Mechanics and Machine Learning for Accelerated Drug Design Against HIV PR Inhibitors
    HENGPHASATPORN Kowit
    SCCJ2023/2023-11-24--2023-11-26
  • Integrated AI-based Modeling and Flexible Docking for Protein-RNA Complexes Refinement
    HENGPHASATPORN Kowit
    BSJ61/2023-11-13--2023-11-16
  • Finding Potent HIV-1 Protease Inhibitors through FMO-Guided Drug Design
    HENGPHASATPORN Kowit
    Chem-Bio Informatics Society(CBI) Annual Meeting 2023/2023-10-23--2023-10-25
  • Inhibition of Dengue Virus by a Sulfonamide Chalcone Targeting the SAM-Binding Site of Viral Methyltransferase
    HENGPHASATPORN Kowit
    「硫黄生物学」第3回領域会議/2023-09-16--2023-09-18
  • FMO-guided design of darunavir analogs as HIV-1 protease inhibitors
    HENGPHASATPORN Kowit
    the 5th Congress of the Theory and Applications of Computational Chemistry (TACC2023)/2023-09-05--2023-09-09
  • Synergistic Integration of FMO and MM Calculations: A Novel Approach for Unveiling Potent Antiviral Agents
    HENGPHASATPORN Kowit
    CU-UM Bilateral Seminar and Workshop/2024-02-17--2024-02-19
  • ドメインスワッピングにより4量化する抗体軽鎖の会合挙動とX線結晶構造
    HENGPHASATPORN Kowit
    2回抗体学会/2023-12-01--2023-12-03
  • 3D structure construction of cyclic peptide using Deep learning
    HENGPHASATPORN Kowit
    the 75th annual meeting of the Society for Biotechnology/2023-09-03--2023-09-05
  • Exploring Antiviral Drug Discovery through Computational Calculations and Fragment Molecular Orbital (FMO) Method
    HENGPHASATPORN Kowit
    CCS – LBNL Collaborative Workshop 2023/2023-04
  • 分子動力学シミュレーションによるがん原因融合タンパク質SS18-SSXのC末端結合領域とヌクレオソームの相互作用解析
    小淵 里恵; 段 炼; Kowit Hengphasatporn; 重田 育照; 谷 一寿; 鈴木 理...
    第46回日本分子生物学会年会/2023-12-06--2023-12-08
  • SOD1のCYS酸化に伴う構造変化の理論的研究
    佐藤 綾香; 藤木 涼; 堀 優太; Hengphasatporn Kowit; 重田 育照
    日本コンピュータ化学会2023年/2023-11-24--2023-11-26
  • 天然変性タンパク質が滑膜肉腫発生の原因となる仕組み
    韓 叡佳; 堀越直樹; 高橋花南; 谷一寿; 宮ノ入洋平; 中本佳歩; 古寺哲幸; Kowit Hengpha...
    第96回日本生化学会大会/2023-10-31--2023-11-2
  • FMO-Guided Design of Darunavir Analogs as HIV-1 Protease Inhibitors
    Hengphasatporn Kowit
    the 5th Congress of the Theory and Applications of Computational Chemistry (TACC2023)/2023-09-5--2023-9-9
  • Combining AI-based Modeling and Flexible Docking for Efficient Refinement of Protein-RNA Complexes using PaCS-MD
    Hengphasatporn Kowit; Nitchakan Darai; Harada Ryuhei; ...
    The Protein Society - 37th Annual Symposium/2023-07-13--2023-07-16
  • 多分野融合によるアミロイド類縁腎臓疾患のメカニズム解析
    HENGPHASATPORN KOWIT
    第40回分子病理学研究会クラークシンポジウム/2023-7-14--2023-7-15
  • 中分子の膜透過性に対する計算手法の検討
    HENGPHASATPORN KOWIT
    日本コンピューター化学会 2022年 秋季年会/2022-11-25--2022-11-27
  • 光合成水分解酸素発生におけるMnの自然選択の理由
    HENGPHASATPORN KOWIT
    量子生命科学会第4回大会/2022-05-26--2022-05-27
  • Evaluation of brominated baicalein as a promising SARs-CoV-2 Mpro Inhibitor
    Hengphasatporn Kowit
    物性研短期研究会「理論タンパク質物性科学の最前線:理論と実験との密な協働/2022-07-26--2022-07-27
  • Evaluation of the Potent SARS-CoV-2 Main Protease Inhibitors using LB-PaCS-MD/FMO Technique
    Hengphasatporn Kowit
    The 60th Annual Meeting of the Biophysical Society of Japan/2022-08-28--2022-08-30
  • Estimation of acid dissociation constants (pKa) of N-containing heterocycles in DMSO and transferability of Gibbs free energy in various solvent conditions
    Hengphasatporn Kowit
    The 6th Asian Workshop on Molecular Spectroscopy(AWMS 2022)/2022-11-3--2022-11-4
  • Integrated Simulation for Antiviral Drug Discovery and Design
    HENGPHASATPORN KOWIT
    The 22nd Annual Meeting of the Protein Science Society of Japan/2023-07-07--2023-07-09
  • Ligand-Binding Mode Evaluation of Potential SARS-CoV-2 Main Protease Inhibitors: LB-PaCS-MD/FMO method
    HENGPHASATPORN KOWIT
    The 25th International Annual Symposium on Computational Science and Engineering (ANSCSE)/2022-07-06--2022-07-09
  • Exploring Antiviral Drug Discovery through Computational Calculations and Fragment Molecular Orbital (FMO) Method
    HENGPHASATPORN KOWIT
    CCS – LBNL Collaborative Workshop 2023/2023-04-12--2023-04-13
  • more...
Talks
  • Computer-aided drug discovery and design
    HENGPHASATPORN Kowit
    Collaborative discussion between the Faculty of Pharmacy, University of Alberta, Canada, and University of Tsukuba, Japan./2024-02-21--2024-02-25

(Last updated: 2024-05-10)