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VILLAREAL MYRA ORLINA(ブリリアル マイラ; Villareal, Myra Orlina)

face
所属
生命環境系
職名
准教授
科研費番号
30619515
eメール
 
研究室
北アフリカ研究センター、共同研究棟A310
電話
029-853-5793
研究分野
分子生物学
応用分子細胞生物学
細胞生物学
研究キーワード
Cell Biology, Food Functionality, Cell differentiation, Pigment cell research, Natural products research
研究課題
Induction of melanocyte stem cells differentiation ...2019-07 -- 2020-06Myra O. Villareal三島海雲記念財団/1,000,000円
モロッコ国及びチュニジア国「エビデンスに基づく乾燥地生物資源シーズ開発による新産業育成研究」2015 -- 2021礒田博子JST/SATREPS/
Valorization of Bio-resources in Semi Arid and Arid Land for Regional Development2009 -- 2013礒田博子/
職歴
2018-11 -- (現在)筑波大学 生命環境系 准教授
2018-04 -- 2018-10産総研 研究員
2014-02 -- 2018-03筑波大学 生命環境系 助教
2011-04 -- 2014-01筑波大学 北アフリカ研究センター 研究員
2004 -- 2007Ateneo de Manila University, Biology Department, Instructor
2000 -- 2004Peter Paul Philippine Corporation Quality Control Department, Quality Control Manager
1995-06 -- 1996-05National Institute of Molecular Biology and Biotechnology (BIOTECH-UPLB),University of the Philippines Los Baños University Research Assoc.
学歴
2008-04 -- 2011-03筑波大学/ 生命環境科学研究科 生物資源科学専攻 博士卒業
1996-06 -- 2000-11Graduate School, University of the Philippines Los Baños Dept. of Microbiology Master of Science in Microbiology卒業
1991-06 -- 1995-03University of the Philippines Los Baños College of Agriculture Bachelor of Science in Agriculture (Soil Microbiology)卒業
取得学位
2011-03博士（農学）筑波大学
2000-11Master of Science in Microbiology (Microbial Genetics)University of the Philippines Los Baños
1995-03Bachelor of Science in Agriculture (Soil Microbiology)University of the Philippines Los Baños
所属学協会
-- (現在)日本細胞生物学会
-- (現在)Society for Medicinal Plants and Natural Products Research
-- (現在)日本色素細胞学会
-- (現在)Philippine Society for Microbiology, Inc.
受賞
2018-11Best Presentation Award, The 31st Annual and International Meeting of JAACT2018 Tsukuba
2016-06-17Teaching Mobility Program Scholarship (Erasmus Mundus)For research activities at the University of Montpellier
2007-04-02MEXT Ph.D. Fellowship at University of Tsukuba
2011-05-15Top 15 Poster Award, European Society for Animal Cell Culture Technology (ESACT) 2011Poster Award
2013Excellent Poster Award, Tsukuba Global Science Week 2013Excellent Poster Award
査読付き学術雑誌・国際会議論文
  • Melanogenesis Promoting Effect, Antioxidant Activity, and UPLC-ESI-HRMS Characterization of Phenolic Compounds of Argan Leaves Extract
    Bourhim Thouria; Villareal Myra Orlina; Couderc François;...
    Molecules, 2021-01
  • Effect of saponin-rich fractions of extracts of argan oil by-products and argan leaves on melanogenesis
    Villareal Myra O.; Chaochaiphat Thanyanan; Makbal Rachida...
    TJASSST Proceedings, 2019-11
  • 3,4,5-tri-O-caffeoylquinic acid (TCQA) as a potential candidate to promote hair growth and melanogenesis
    Bejaoui Meriem; Villareal Myra O.; Isoda Hiroko
    TJASSST Proceedings, 2019-09
  • The Wnt/ β-catenin signaling pathway mediated hair growth and pigmentation promotion effect of 3,4,5-tri-O-caffeoylquinic acid
    Bejaoui Meriem; Villareal Myra Orlina; Isoda Hiroko
    Pigment Cell and Melanoma Research, 2019-09
  • Lupenone from Erica multiflora leaf extract stimulates melanogenesis in B16 murine melanoma cells through the inhibition of ERK1/2 activation
    Villareal Myra Orlina; Han Junkyu; Matsuyama Kyoko; Sekii...
    Planta Medica, 2013-03
  • Caffeoylquinic Acid-Rich Purple Sweet Potato Extract, with or without Anthocyanin, Imparts Neuroprotection and Contributes to the Improvement of Spatial Learning and Memory of SAMP8 Mouse
    Sasaki Kazunori; Han Junkyu; Hidetoshi Shimozono; Villare...
    Journal of agricultural and food chemistry, 2013-05
  • Acteoside inhibits type Ι allergy through the down-regulation of Ca/NFAT and JNK MAPK signaling pathways in basophilic cells
    Motojima Hideko; Villareal Myra O; Iijima Rieko; Han Junk...
    Journal of natural medicines, 2013-10
  • Effect of Olive Leaf Components on the Expansion of Human Hematopoietic Stem and Progenitor Cells
    Samet Imen; Villareal Myra O; Junkyu Han; Sayadi Sami; Is...
    Asian Journal Biomed. Pharm. Sci., 2014-04
  • Analysis of the erythroid differentiation effect of flavonoid apigenin on K562 human chronic leukemia cells
    Isoda Hiroko; Motojima Hideko; Onaga Shoko; Samet Imen; V...
    Chemico-biological interactions, 2014-09
  • The Type 2 diabetes-preventive effect of cyanidin-3-glucoside on adipocytes
    Matsukawa Toshiya; Villareal Myra O; Isoda Hiroko
    Journal of Developments in Sustainable Agriculture, 2016-11
  • Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer
    Iwasaki Kenichi; Zheng Yun-Wen; Murata Soichiro; Ito Hiro...
    World journal of gastroenterology, 2016-11
  • Increasing cAMP levels of preadipocytes by cyanidin-3-glucoside treatment induces the formation of beige phenotypes in 3T3-L1 adipocytes
    Matsukawa Toshiya; Villareal Myra O; Motojima Hideko; Iso...
    The Journal of nutritional biochemistry, 2017-02
  • Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
    Villareal Myra Orlina; Ikeya Ayumi; Sasaki Kazunori; Arfa...
    BMC complementary and alternative medicine, 2017-12
  • Daphnane diterpenes inhibit the metastatic potential of B16F10 murine melanoma cells in vitro and in vivo
    Villareal Myra Orlina; Sato Yuki; Matsuyama Kyoko; Isoda ...
    BMC Cancer, 2018-08
  • Depigmenting effect of argan press-cake extract through the down-regulation of Mitf and melanogenic enzymes expression in B16 murine melanoma cells
    Bourhim Thouria; Villareal Myra Orlina; Gadhi Chemseddoha...
    Cytotechnology, 2018-10
  • β-catenin-mediated hair growth induction effect of 3, 4, 5-tri-O-caffeoylquinic acid
    Bejaoui Meriem; Villareal Myra Orlina; Isoda Hiroko
    Aging, 2019-06
  • 3, 4, 5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
    Bejaoui Meriem; Villareal Myra Orlina; Isoda Hiroko
    Frontiers in Cell and Developmental Biology, 2020-03
  • Argania Spinosa Fruit Shell Extract-Induced Melanogenesis via cAMP Signaling Pathway Activation
    Makbal Rachida; Villareal Myra; Gadhi Chemseddoha; Abdell...
    International Journal of Molecular Sciences, 2020-01
  • Elucidation of the effect of plumbagin on the metastatic potential of B16F10 murine melanoma cells via MAPK signalling pathway
    Alem Fatima‐Zahra; Bejaoui Meriem; Villareal Myra Orlina;...
    Experimental Dermatology, 2020-04
  • Tara Tannin Regulates Pigmentation by Modulating Melanogenesis Enzymes and Melanosome Transport Proteins Expression
    Villareal Myra Orlina; Chaochaiphat Thanyanan; Bejaoui Me...
    Planta Medica International Open, 2020-04
  • Varietal effect on the concentration and anti-inflammatory activity of hydroxytyrosol in French olive oils
    Almaksour Ziad; Boudard Frederic; Kelly Mary; Puljate Igo...
    Journal of Medicinal Food/Epub, 2020-05
    PubMed
  • L-Citrulline Supplementation-Increased Skeletal Muscle PGC-1α Expression is Associated With Exercise Performance and Increased Skeletal Muscle Weight
    Villareal Myra O; Matsukawa Toshiya; Isoda Hiroko
    Molecular nutrition & food research/62(14), 2018-05
    PubMed Tsukuba Repository
  • Anti-inflammatory and antioxidant activities of different extra virgin olive oil varieties extracts
    Almaksour Z. Boudard F. Grosmaire L. Guzman C. Larroque M...
    Arabian Journal of Medicinal & Aromatic Plants/(2017 V3 N(2) 183), 2017-06
  • Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species
    Nakayama K; Murata Soichiro; Ito Hiromu; Iwasaki Kenichi;...
    Oncology Letters./14(2)/pp.2015-2024, 2017-06
    PubMed Tsukuba Repository
  • Hirseins inhibit melanogenesis by regulating the gene expressions of Mitf and melanogenesis enzymes
    Villareal Myra Orlina; Han Junkyu; Yamada Parida; Shigemo...
    Experimental Dermatology, 2010-05
more...
その他の論文・記事
著書
  • Comparative genome plasticity of tomato and banana strains of Ralstonia solanacearum in the Philippines
    VILLAREAL MYRA ORLINA; Auncion K. Raymundo Myra Orlina-Vi...
    Bacterial wilt disease and the Ralstonia solanacearum species complex, 2005
  • Harnessing the Potential of North African and Mediterranean Bioresources for the Regulation of Signal Transduction in Melanogenesis and Cancer Cell Differentiation
    Villareal Myra Orlina
    Sustainable North African Society: Exploring Seeds and Resources for Innovation, 2014
  • Caffeic Acid and its Biological Effects on Brain Function.
    Villareal Myra Orlina; Sato Yuki; Isoda Hiroko
    Health Benefits Of Green Coffee Bean In Human, Taylor and Francis, 2016
会議発表等
  • Natural products regulate melanogenesis by targetting MITF
    Villareal Myra Orlina; Isoda Hiroko
    2020 APAMS Annual Scientific Meeting/2020-07-20--2020-08-14
  • Regulation of Melanogenesis using Natural Compounds
    Villareal Myra Orlina
    DAILAB PIKNIH Series XXXVII. October 7, 2019/2019-10-05--2019-10-07
  • Melanogenesis regulatory effects of Mediterranean and North African plants and their bioactive components.
    Villareal Myra Orlina; Isoda Hiroko
    The 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT)/2018-11-05--2018-11-08
  • Elucidation of the hair growth promoting effects of 3,4,5-tri-O-caffeoylquinic acid (TCQA)
    Bejaoui Meriem; Villareal Myra O.; Isoda Hiroko
    The 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT)/2018-11-05--2018-11-08
  • Natural Products Regulate Melanogenesis By Targeting MITF
    Villareal Myra Orlina; Isoda Hiroko
    40th PAASE Anniversary and 2020 APAMS/2020-07-20--2020-08-14
  • Effect of saponin-rich fractions of extracts of argan oil by-products and argan leaves on melanogenesis
    Villareal Myra O.; Chaochaiphat Thanyanan; Makbal Rachida...
    Tunisia-Japan Symposium on Science , Society and Technology (TJASSST)/2019-11-29--2019-12-02
  • 3,4,5-tri-O-caffeoylquinic acid (TCQA) as a potential candidate to promote hair growth and melanogenesi
    Bejaoui Meriem; Villareal Myra Orlina; Isoda Hiroko
    Tunisia-Japan Symposium on Science , Society and Technology (TJASSST)/2019-11-29--2019-12-02
  • The Wnt/ β-catenin signaling pathway mediated hair growth and pigmentation promotion effect of 3,4,5-tri-O-caffeoylquinic acid
    Bejaoui Meriem; Villareal Myra Orlina; Isoda Hiroko
    European Society for Pigment Cell Research (ESPCR)/2019-09-12--2019-09-14
  • Experiences, ideas, and networking: Life Science solutions to global challenges in the context of Society 5.0 and SDGs
    Villareal Myra Orlina
    Tsukuba Conference 2019/2019-10-02--2019-10-04
  • 3,4,5-tri-O-caffeoylquinic acid as a potential candidate to induce hair growth and hair pigmentation
    Bejaoui Meriem; Orlina VILLAREAL Myra; Isoda Hiroko
    Tunisia-Japan Symposium on Science, Society and Technology (TJASSST 2017)/2017-11-24--2017-11-26
  • Melanogenesis Regulatory effect of argan (Argan spinosa) oil and by-products from argan fruit on melanogenesis in B16 murine melanoma cells
    Orlina VILLAREAL Myra; Isoda Hiroko
    Tunisia-Japan Symposium on Science, Society and Technology (TJASSST 2017, Gammarth, Tunisia),/2017-11-24--2017-11-26
  • Effect of certain byproducts of the Argan tree on hyper pigmentation of the skin
    Bourhim T. Makbal R. Hafidi A. Gadhi C.; Orlina VILLAREA...
    4th edition of the Argan International Congress/2017-11-20--2017-11-22
  • Molecular basis of the lightening effect on the skin of Argan oil and some by-products of the Argan
    Bourhim T. Makbal R. Hafidi A. Gadhi C.; VILLAREAL Myra O...
    1st International Symposium on the beneficial effects of Argan oil on human health/2017-05-04--2017-05-06
  • In vitro and in vivo Anti-Melanoma Effect of T. hirsuta Extract and Its Bioactive Component Daphnane Diterpenoid Gnidilatidin
    Orlina VILLAREAL Myra; Sato; Isoda Hiroko
    International Pigment Cell Conference/2017-08-26--2017-08-30
  • Anti-melanoma effects of natural products from olives (Olea europaea) in vitro
    Villareal Myra Orlina; Isoda Hiroko
    TJASSST 2015/2016-02
  • Oxidative-stress targeted anti-melanoma effects of Cymbopogon schoenanthus
    Myra O. Villareal; Sakura Maezono; Mai Maeda; Mohamed Nef...
    The 27th Annual Meeting of Japanese Association for Animal Cell Technology (JAACT2014 Kitakyushu)/2014-11-11--2014-11-14
  • Essential oil of Mediterranean Rosmarinus officinalis L. shows anti-stress effect by inducing neuronal differentiation
    Ayumi Ikeya; Junkyu Han; Myra O. Villareal; Mohamed Neffa...
    The 27th Annual Meeting of Japanese Association for Animal Cell Technology (JAACT2014 Kitakyushu)/2014-11-11--2014-11-14
  • Anti-allergy and melanogenesis regulatory effects of semi-arid and arid land plants
    Huichia CHAO; Konomi MURAKAMI; Hanen NAJJA; Hideko MOTOJI...
    Second International Conference on Arid Land Studies (ICAL2)/2014-09-10--2014-09-14
  • Diterpenoid Hirsein-A Activate Nuclear P38 Through GADD45b Upregulation: Possible Route For Induction Of Melanoma Cell
    M. Villareal; Isoda Hiroko
    XXII International Pigment Cell Conference (IPCC2014)/2014-09-04--2014-09-07
  • Suppressive effect of Caffeic acid and Caffeic Acid Phenethyl Ester on Oxidative Stress in B16 Mouse Melanoma and Human Epidermal Melanocytes
    Sakura Eri B. Maezono; Myra O. Villareal; Junkyu Han; Iso...
    The XXVIIth International Conference on Polyphenols & The 8th Tannin Conference (ICP2014 Nagoya)/2014-09-02--2014-09-06
  • The metabolism-enhancement effect of cyanidin-3-glucoside derived from black soybean in C2C12 myotubes
    Toshiya Matsukawa; Myra O. Villareal; Junkyu Han; Masaya ...
    The XXVIIth International Conference on Polyphenols & The 8th Tannin Conference (ICP2014 Nagoya)/2014-09-02--2014-09-06
  • Apigenin inhibits type I allergic reaction in RBL-2H3 cells through the mitogen-activated protein kinase pathway
    Hideko Motojima; Myra O. Villareal; Junkyu Han; Isoda Hiroko
    The XXVIIth International Conference on Polyphenols & The 8th Tannin Conference (ICP2014 Nagoya)/2014-09-02--2014-09-06
  • Inhibitory effect of caffeic acid and its derivative, caffeic acid phenethyl ester on oxidative stress in human epidermal melanocytes
    Maezono S.; Villareal M.O.; Han J.; Isoda Hiroko
    先導的研究者体験者プログラム（ARE）第3回リサーチフェスタ
  • Regulatory effect of terpene compounds on melanogenesis signal transduction pathways in B16 murine melanoma cells
    Villareal M.O.; Han J.; Shigemori H.; H. Isoda
    日本農芸化学会2014年度大会/2014-03-28--2014-03-30
担当授業科目
2020-04 -- 2020-08環境科学研究1S筑波大学
2020-04 -- 2020-08環境科学セミナー1S筑波大学
2020-10 -- 2021-02環境科学研究1F筑波大学
2020-10 -- 2021-02環境科学セミナー1F筑波大学
2020-11 -- 2020-11環境学フォーラムII筑波大学
2020-04 -- 2020-08Internship in Environmental Studies III [English class] (環境学実践実習III)筑波大学
2020-10 -- 2021-02Internship in Environmental Studies III [English class] (環境学実践実習III)筑波大学
2020-10 -- 2021-03ライフイノベーション博士後期演習III秋筑波大学
2020-10 -- 2021-02Seminar in Environmental Sciences 1F筑波大学
2020-10 -- 2021-02環境学実践実習II筑波大学
more...
一般講演
  • Report on TLSI Session: Experiences, ideas, and networking: Life Science solutions to global challenges in the context of Society 5.0 and SDGs
    Villareal Myra Orlina
    Tsukuba Global Science Week 2020 (Session 3: Tsukuba Conference Session – Perspectives on global challenges in attaining Society 5.0 and SDGs)/2020-09-28--2020-09-30
  • Determination of the effect of argan oil and its by-products on melanogenesis in vitro
    Villareal Myra Orlina; Isoda Hiroko
    International symposium on Medicinal and Aromatic Plants (SIPAM)/2017-03-16--2017-03-18
学内管理運営業績
2018-11 -- (現在)ライフイノベーション学位プログラム運営委員会員委員
2018-11 -- (現在)ライフイノベーション学位プログラム国際連携委員会委員
2018-11 -- (現在)ライフイノベーション学位プログラム学生支援委員会委員長
2018-11 -- (現在)大学院環境科学専攻SUSTEP英語教育プログラム委員会委員
その他の活動
2018-11 -- (現在)筑波大学　地中海・北アフリカ研究センター Member

(最終更新日: 2021-02-08)