伊関 大敬(イセキ ヒロヨシ; Iseki, Hiroyoshi)

所属

国際統合睡眠医科学研究機構

職名

助教

研究課題

エピゲノム研究を革新する統合的エピゲノム制御システムの開発と個体モデルの創出

2017 -- 2019

伊関 大敬

日本学術振興会/基盤研究(C)

4,810,000円

取得学位

博士（医学）

筑波大学

論文

• Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling
  Iseki Hiroyoshi; Takeda Akihiko; Andoh Toshiwo; Takahashi...
  Cancer science/101(6)/pp.1361-1366, 2010-06
  PubMed
• von Willebrand factor type D domain mutant of SVS-1/SUSD2, vWD(m), induces apoptosis in HeLa cells
  Sugahara Tetsuo; Yamashita Yzumi; Shinomi Masahito; Isobe...
  Cancer science/98(6)/pp.909-915, 2007-06
  PubMed
• Clinical significance of large tenascin-C spliced variant as a potential biomarker for colorectal cancer
  Takeda Akihiko; Otani Yoshihide; Iseki Hiroyoshi; Takeuch...
  World journal of surgery/31(2)/pp.388-394, 2007-02
  PubMed
• Establishment and characterization of the human SaTM-1 anal canal squamous cell carcinoma cell line derived from lymph node metastasis
  Takeda Akihiko; Maeda Masahiro; Iseki Hiroyoshi; Hirooka ...
  International journal of molecular medicine/24(4)/pp.465-472, 2009-10
  PubMed
• Isolation of a novel mouse gene, mSVS-1/SUSD2, reversing tumorigenic phenotypes of cancer cells in vitro
  Sugahara Tetsuo; Yamashita Yzumi; Shinomi Masahito; Yaman...
  Cancer science/98(6)/pp.900-908, 2007-06
  PubMed
• Sirt1, p53, and p38(MAPK) are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation
  Hishida Tomoaki; Nozaki Yuriko; Nakachi Yutaka; Mizuno Yo...
  Stem cells (Dayton, Ohio)/30(8)/pp.1634-1644, 2012-08-01
  PubMed
• ALEX1 suppresses colony formation ability of human colorectal carcinoma cell lines
  Iseki Hiroyoshi; Takeda Akihiko; Andoh Toshiwo; Kuwabara ...
  Cancer science/103(7)/pp.1267-1271, 2012-07
  PubMed
• Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes
  Tanisawa Kumpei; Mikami Eri; Fuku Noriyuki; Honda Yoko; H...
  BMC genomics/14/p.248, 2013-04
  PubMed
• Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.
  Sugiyama Fumihiro; Iseki Hiroyoshi
  Stem Cells/34(2)/pp.322-333, 2015-11
  PubMed
• Generation of CRISPR/Cas9-mediated bicistronic knock-in Ins1-cre driver mice
  HASEGAWA Yoshikazu; HOSHINO Yoshikazu; IBRAHIM Abdelaziz ...
  Experimental Animals/65(3)/pp.319-327, 2016-07
  CiNii PubMed Tsukuba Repository
• Truncated Cables1 causes agenesis of the corpus callosum in mice.
  Mizuno S; Tra DT; Mizobuchi A; Iseki Hiroyoshi; Mizuno-Ii...
  Laboratory investigation; a journal of technical methods and pathology/94(3)/pp.321-330, 2013-12
  PubMed
• Propagation of rat parvovirus in thymic lymphoma cell line C58(NT)d and subsequent appearance of a resistant cell clone after lytic infection
  Ueno Y; Harada T; Iseki Hiroyoshi; Ohshima T; Sugiyama F;...
  J Virol/75(8)/pp.3965-3970, 2001-01
  PubMed
• A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice
  Mizuno Seiya; Mizobuchi Atsushi; Iseki Hiroyoshi; Iijima ...
  MAMMALIAN GENOME/21(11-12)/pp.525-533, 2010-12
  PubMed
• Establishment of a new embryonic stem cell line derived from C57BL/6 mouse expressing EGFP ubiquitously
  Shimizukawa R; Sakata A; Hirose M; Takahashi A; Iseki Hir...
  GENESIS/42(1)/pp.47-52, 2005-05
  PubMed
• Parvovirus nonstructural proteins induce an epigenetic modification through histone acetylation in host genes and revert tumor malignancy to benignancy
  Iseki Hiroyoshi; Shimizukawa R; Sugiyama F; Kunita S; Iwa...
  JOURNAL OF VIROLOGY/79(14)/pp.8886-8893, 2005-07
  PubMed
• A novel subpopulation lacking Oct4 expression in the testicular side population
  Shimizu Y; Motohashi N; Iseki Hiroyoshi; Kunita S; Sugiya...
  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE/17(1)/pp.21-28, 2006-01
  PubMed
• Development of ELISA using recombinant antigens for specific detection of mouse parvovirus infection
  Kunita S; Chaya M; Hagiwara K; Ishida T; Takakura A; Sugi...
  EXPERIMENTAL ANIMALS/55(2)/pp.117-124, 2006-04
  PubMed

(最終更新日: 2020-07-14)