吉野 龍ノ介(ヨシノ リュウノスケ; Yoshino, Ryunosuke)

所属

医学医療系

職名

助教

研究キーワード

計算化学、分子シミュレーション

研究課題

FMO法による相互作用解析情報を用いたファーマコフォアモデリングの提案

2018 -- 2019

吉野 龍ノ介

日本学術振興会/若手研究

2,080,000円

職歴

2017-04 -- 2018-03

東京工業大学 情報生命博士教育院 特任助教

取得学位

2017-03

博士（農学）

東京大学大学院農学生命科学研究科

査読付き学術雑誌・国際会議論文

• An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
  Koiwai Kotaro; Inaba Kazue; Morohashi Kana; Enya Sora; Ar...
  Journal of Biological Chemistry/295(20)/pp.7154-7167, 2020-05
  PubMed
• A prospective compound screening contest identified broader inhibitors for Sirtuin 1
  Chiba Shuntaro; Ohue Masahito; Gryniukova Anastasiia; Bor...
  Scientific reports/9, 2019-12
  PubMed
• Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil
  Yoshino Ryunosuke; Yasuo Nobuaki; Sekijima Masakazu
  Scientific reports/9, 2019-11
  PubMed
• Temperature-pressure shuffling outlier flooding method enhances the conformational sampling of proteins
  Harada Ryuhei; Yoshino Ryunosuke; Nishizawa Hiroaki; Shig...
  Journal of computational chemistry/40(15)/pp.1530-1537, 2019-02
  PubMed
• Compound property enhancement by virtual compound synthesis
  Arai Naoki; Yoshikawa Shunsuke; Yasuo Nobuaki; Yoshino Ry...
  Journal of Bioinformatics and Computational Biology/16(3), 2018-6
  PubMed
• Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach
  Naoki Wakuia; Ryunosuke Yoshino; Yoshino Ryunosuke; Nobua...
  Journal of Molecular Graphics and Modelling/79/pp.166-174, 2018-1
  PubMed
• An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
  Shuntaro Chiba; Takashi Ishida; Kazuyoshi Ikeda; Masahiro...
  Scientific Reports/7, 2017-9
  PubMed
• In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
  Yoshino Ryunosuke; Nobuaki Yasuo; Yohsuke Hagiwara; Takas...
  Scientific Reports/7, 2017-7
  PubMed
• Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target.
  Shuntaro Chiba; Kazuyoshi Ikeda; Takashi Ishida; M. Micha...
  Scientific Reports/5, 2015-11
  PubMed
• Pharmacophore modeling for anti-Chagas drug design using the fragment molecular orbital method.
  Yoshino Ryunosuke; Nobuaki Yasuo; Daniel Ken Inaoka; Yohs...
  PLoS One, 2015-5
  PubMed

その他の論文・記事

• Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates
  Yoshino Ryunosuke; Yasuo Nobuaki; Sekijima Masakazu
  SCIENTIFIC REPORTS/10(1), 2020-07
  PubMed
• Parallel cascade selection molecular dynamics to screen for protein complexes generated by rigid docking
  Harada Ryuhei; Yoshino Ryunosuke; Nishizawa Hiroaki; Shig...
  Journal of molecular graphics & modelling/92/pp.94-99, 2019-07
  PubMed

会議発表等

• 昆虫ステロイドホルモン生合成に必要なグルタチオンS -転移酵素Noppera-boの 阻害剤探索
  海老原 佳奈; 稲葉 和恵; 小祝 孝太郎; 吉野 龍ノ介; 広川 貴...
  日本結晶学会 令和2年(2020年)度年会/2020-11-27--2020-11-28
• 環状ペプチドにおける、溶媒の違いによる構造変化と自由エネルギー安定性の評価
  柳 昂輝; 重田 育照; 西澤 宏晃; 原田 隆平; 吉野 龍ノ介; 満...
  日本コンピュータ化学会2019秋季年会/2019-10-24--2019-10-25
• 環状ジペプチドの安定構造における系統的な傾向と特徴
  栁 昂輝; 西澤 宏晃; 吉野 龍ノ介; 原田 隆平; 重田 育照
  第57回日本生物物理学会年会/2019-09-24--2019-09-26
• Combined experimental and computational approaches reveal a unique structural property of the Halloween glutathione S-transferase Noppera-bo
  Koiwai Kotaro; Inaba Kazue; Morohashi Kana; Enya Sora; Im...
  4th International Insect Hormone Workshop/2019-07-01--2019-07-01
• Discovery of a novel inhibitor of spermidine synthase for Chagas' disease by molecular dynamics and docking simulation
  Yoshino Ryunosuke
  Asia Hub for e-Drug Discovery Symposium/2018-09-26--2018-09-29
• In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
  Yoshino Ryunosuke
  4th IITM – Tokyo Tech Joint Symposium titled Frontiers in Bioinformatics: Large scale data analysis, Resources and Drug design/2017-11-10--2017-11-11
• Compound Property Enhancer by Virtual Compound Synthesis
  Naoki Arai; Shunsuke Yoshikawa; Nobuaki Yasuo; Yoshino Ry...
  The 28th International Conference on Genome Informatics GIW/BIOINFO 2017/2017-10-31--2017-11-3

(最終更新日: 2020-10-19)