広川 貴次(ヒロカワ タカツグ)
- 論文
- Site-Directed Chemical Mutations on Abzymes: Large Rate Accelerations in the Catalysis by Exchanging the Functionalized Small Nonprotein Components
Ishikawa Fumihiro; Shirahashi Masato; Hayakawa Hiroshi...
ACS chemical biology/11(10)/pp.2803-2811, 2016-04 - Tailored Synthesis of 162-Residue S-Monoglycosylated GM2-Activator Protein (GM2AP) Analogues that Allows Facile Access to a Protein Library
Nakamura Takahiro; Sato Kohei; Naruse Naoto; Kitakaze ...
Chembiochem : a European journal of chemical biology/17(20)/pp.1986-1992, 2016-04 - Differences in Intestinal Hydrolytic Activities between Cynomolgus Monkeys and Humans: Evaluation of Substrate Specificities Using Recombinant Carboxylesterase 2 Isozymes
Igawa Yoshiyuki; Fujiwara Seiya; Ohura Kayoko; Hirokaw...
Molecular pharmaceutics/13(9)/pp.3176-3186, 2016-04 - Design and synthesis of unsymmetric macrocyclic hexaoxazole compounds with an ability to induce distinct G-quadruplex topologies in telomeric DNA
Sakuma Mai; Ma Yue; Tsushima Yamato; Iida Keisuke; Hi...
Organic & biomolecular chemistry/14(22)/pp.5109-5116, 2016-06 - An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
Koiwai Kotaro; Inaba Kazue; Morohashi Kana; Enya Sora; Ar...
Journal of Biological Chemistry/295(20)/pp.7154-7167, 2020-05 - A prospective compound screening contest identified broader inhibitors for Sirtuin 1
Chiba Shuntaro; Ohue Masahito; Gryniukova Anastasiia; ...
Scientific reports/9, 2019-12 - Synthesis of C12-keto saxitoxin derivatives with unusual inhibitory activity against voltage-gated sodium channels
Adachi Kanna; Yamada Tomoshi; Ishizuka Hayate; Oki Mana; ...
Chemistry (Weinheim an der Bergstrasse, Germany)/26(9)/pp.2025-2033, 2019-11 - Unnatural Tripeptides as Potent Positive Allosteric Modulators of T1R2/T1R3
Yamada Kei; Nakazawa Masakazu; Matsumoto Kayo; Tagami Un...
ACS medicinal chemistry letters, 2019-03 - Unnatural Tripeptides as Potent Positive Allosteric Modulators of T1R2/T1R3
Yamada Kei; Nakazawa Masakazu; Matsumoto Kayo; Tagami Un...
ACS medicinal chemistry letters/10(5)/pp.800-805, 2019-05-09 - Total Synthesis and Characterization of Thielocin B1 as a Protein－Protein Interaction Inhibitor of PAC3 Homodimer
Doi Takayuki; Yoshida Masahito; Ohsawa Kosuke; Shin-ya K...
Chemical Science/5/pp.1860-1868, 2014-01 - A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis
Ito Shinya; Ogawa Koji; Takeuchi Koh; Yoshida Masahito; T...
The Journal of Biological Chemistry/292(49)/pp.20076-20085, 2017-12 - Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor
Nakagita Tomoya; Ishida Akiko; Matsuya Takumi; Kobayas...
PloS one/14(3), 2019-03 - EFCAB2 is a novel calcium-binding protein in mouse testis and sperm
Shawki Hossam H; Ishikawa-Yamauchi Yu; Kawashima Akihiro...
PloS one/14(4), 2019-04 - Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly
Sakaue Haruka; Shiota Takuya; Ishizaka Naoya; Kawano ...
Molecular cell/73(5)/p.1044-1055.e8, 2019-03 - Stratifin inhibits SCFFBW7 formation and blocks ubiquitination of oncoproteins during the course of lung adenocarcinogenesis
Shiba-Ishii Aya; Hong Jeongmin; Hirokawa Takatsugu; Kim ...
Clinical cancer research : an official journal of the American Association for Cancer Research/25(9)/pp.2809-2820, 2019-02-06 - Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains
Ma Yue; Iida Keisuke; Sasaki Shogo; Hirokawa Takatsug...
Molecules (Basel, Switzerland)/24(2), 2019-01 - The Novel SFN Inhibitors Aprepitant and Ticagrelor Exert Anti-Tumor Effects Through Blocking of Oncoprotein Ubiquitination
Shiba A.; Hong J.; Hirokawa T.; Kim Y.; Noguchil M.
JOURNAL OF THORACIC ONCOLOGY/13(10::S)/pp.S519-S519, 2018-10 - Ligand binding to human prostaglandin E receptor EP at the lipid-bilayer interface
Toyoda Yosuke; Morimoto Kazushi; Suno Ryoji; Horita S...
Nature chemical biology/15(1)/pp.18-26, 2019-01 - Synthesis and biological evaluation of thielocin B1 analogues as protein-protein interaction inhibitors of PAC3 homodimer
Ohsawa Kosuke; Yoshida Masahito; Izumikawa Miho; Takagi ...
Bioorganic & Medicinal Chemistry/26(23-24)/pp.6023-6034, 2018-12 - Development of G-quadruplex ligands for selective induction of a parallel-type topology
Ma Yue; Tsushima Yamato; Sakuma Mai; Sasaki Shogo; Ii...
Organic & biomolecular chemistry/16(40)/pp.7375-7382, 2018-09 - An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
Shuntaro Chiba; Takashi Ishida; Kazuyoshi Ikeda; Masahiro Mo...
Scientific Reports/7, 2017-9 - Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Suno Ryoji; Kimura Kanako Terakado; Nakane Takanori; Y...
Structure (London, England : 1993)/26(1)/pp.7-+, 2017-11 - Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
Okamoto Naoki; Mizote Keisuke; Honda Hiroe; Saeki Aki...
The Journal of biological chemistry/292(37)/pp.15378-15394, 2017-09 - Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock
Shinohara Yuta; Koyama Yohei M; Ukai-Tadenuma Maki; Hi...
Molecular cell/67(5)/p.783-798.e20, 2017-09 - An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
Chiba Shuntaro; Ishida Takashi; Ikeda Kazuyoshi; Mochi...
Scientific reports/7(1), 2017-09 - さらに表示...
- Site-Directed Chemical Mutations on Abzymes: Large Rate Accelerations in the Catalysis by Exchanging the Functionalized Small Nonprotein Components