広川 貴次(ヒロカワ タカツグ)
- 論文
- MDContactCom: a tool to identify differences of protein molecular dynamics from two MD simulation trajectories in terms of interresidue contacts
Motono Chie; Yanagida Shunsuke; Sato Miwa; Hirokawa Taka...
BIOINFORMATICS/38(1)/pp.273-274, 2022-01 - Evaluating cepharanthine analogues as natural drugs against SARS-CoV-2
Hijikata Atsushi; Shionyu-Mitsuyama Clara; Nakae Setsu...
FEBS OPEN BIO/12(1)/pp.285-294, 2022-01 - Heme-dependent recognition of 5-aminolevulinate synthase by the human mitochondrial molecular chaperone ClpX
Nomura Kazumi; Kitagawa Yu; Aihara Marina; Ohki Yusuke; F...
FEBS LETTERS/595(24)/pp.3019-3029, 2021-12 - 2-Carba-lysophosphatidic acid is a novel beta-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition
Fukasawa Keiko; Gotoh Mari; Uwamizu Akiharu; Hirokawa ...
SCIENTIFIC REPORTS/11(1), 2021-08 - Vinylnaphthalene-bearing hexaoxazole as a fluorescence turn-on type G-quadruplex ligand
Ma Yue; Wakabayashi Yuki; Watatani Naruyuki; Saito Ry...
ORGANIC & BIOMOLECULAR CHEMISTRY/19(37)/pp.8035-8040, 2021-10 - The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis
Sekiya Motohiro; Kainoh Kenta; Sugasawa Takehito; Yosh...
Nature communications/12(1)/p.6315, 2021-11 - JBIR-155, a Specific Class D beta-Lactamase Inhibitor of Microbial Origin
Nishimura Takehiro; Kawahara Teppei; Kagaya Noritaka; ...
ORGANIC LETTERS/23(11)/pp.4415-4419, 2021-06 - Structural Insights into the Interaction of Filovirus Glycoproteins with the Endosomal Receptor Niemann-Pick C1: A Computational Study
Igarashi Manabu; Hirokawa Takatsugu; Takadate Yoshihir...
VIRUSES-BASEL/13(5), 2021-05 - Protein druggability assessment for natural products using in silico simulation: A case study with estrogen receptor and the flavonoid genistein
Ohbuchi Katsuya; Hirokawa Takatsugu
Gene/791, 2021-05 - Structural insights from an in silico molecular docking simulation of complement component 3a receptor 1 with an antagonist
Misawa Kensuke; Sugai Yoshiya; Fujimori Taketoshi; Hiroka...
Journal of molecular graphics & modelling/106, 2021-04 - Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment
Ohashi Hirofumi; Watashi Koichi; Saso Wakana; Shionoya...
iScience/24(4), 2021-03 - Current Challenges and Opportunities in Designing Protein-Protein Interaction Targeted Drugs
Shin Woong-Hee; Kumazawa Keiko; Imai Kenichiro; Hiroka...
Advances and applications in bioinformatics and chemistry : AABC/13/pp.11-25, 2020-04-01 - Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo
Koiwai Kotaro; Morohashi Kana; Inaba Kazue; Ebihara Kana...
Journal of Pesticide Science/46(1-2)/pp.75-87, 2021-01 - Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex
Sasaki Shogo; Ma Yue; Ishizuka Takumi; Bao Hong-Liang...
RSC ADVANCES/10(71)/pp.43319-43323, 2020-12 - Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo
Sakamoto Kotaro; Masutani Teruaki; Hirokawa Takatsugu
SCIENTIFIC REPORTS/10(1), 2020-12 - SYNTHESIS AND BIOLOGICAL EVALUATION OF NMDI14 DERIVATIVES AS ANTI-MESOTHELIOMA AGENTS
Hong Nhung Nguyen; Suzuki Koya; Kimura Yasuaki; Hiroka...
HETEROCYCLES/100(2)/pp.253-266, 2020-02 - Ibuprofen, a nonsteroidal anti-inflammatory drug, is a potent inhibitor of the human sweet taste receptor
Nakagita Tomoya; Taketani Chiaki; Narukawa Masataka; H...
Chemical senses/45(8)/pp.667-673, 2020-10 - Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional
Toda Yasuka; Nakagita Tomoya; Hirokawa Takatsugu; Yama...
Scientific reports/8(1), 2018-04 - Ligand-Phospholipid Conjugation: A Versatile Strategy for Developing Long-Acting Ligands That Bind to Membrane Proteins by Restricting the Subcellular Localization of the Ligand
Kawamura Shuhei; Ito Yoshihiko; Hirokawa Takatsugu; Hi...
Journal of medicinal chemistry/61(9)/pp.4020-4029, 2018-04 - Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3
Komiyama Tomoyoshi; Ogura Atsushi; Hirokawa Takatsugu; ...
International journal of molecular sciences/18(1), 2016-12 - Site-Directed Chemical Mutations on Abzymes: Large Rate Accelerations in the Catalysis by Exchanging the Functionalized Small Nonprotein Components
Ishikawa Fumihiro; Shirahashi Masato; Hayakawa Hiroshi...
ACS chemical biology/11(10)/pp.2803-2811, 2016-04 - Tailored Synthesis of 162-Residue S-Monoglycosylated GM2-Activator Protein (GM2AP) Analogues that Allows Facile Access to a Protein Library
Nakamura Takahiro; Sato Kohei; Naruse Naoto; Kitakaze ...
Chembiochem : a European journal of chemical biology/17(20)/pp.1986-1992, 2016-04 - Differences in Intestinal Hydrolytic Activities between Cynomolgus Monkeys and Humans: Evaluation of Substrate Specificities Using Recombinant Carboxylesterase 2 Isozymes
Igawa Yoshiyuki; Fujiwara Seiya; Ohura Kayoko; Hirokaw...
Molecular pharmaceutics/13(9)/pp.3176-3186, 2016-04 - Design and synthesis of unsymmetric macrocyclic hexaoxazole compounds with an ability to induce distinct G-quadruplex topologies in telomeric DNA
Sakuma Mai; Ma Yue; Tsushima Yamato; Iida Keisuke; Hi...
Organic & biomolecular chemistry/14(22)/pp.5109-5116, 2016-06 - An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
Koiwai Kotaro; Inaba Kazue; Morohashi Kana; Enya Sora; Ar...
Journal of Biological Chemistry/295(20)/pp.7154-7167, 2020-05 - さらに表示...
- MDContactCom: a tool to identify differences of protein molecular dynamics from two MD simulation trajectories in terms of interresidue contacts