広川 貴次(ヒロカワ タカツグ)
- 論文
- Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly
Sakaue Haruka; Shiota Takuya; Ishizaka Naoya; Kawano ...
Molecular cell/73(5)/p.1044-1055.e8, 2019-03 - Stratifin inhibits SCFFBW7 formation and blocks ubiquitination of oncoproteins during the course of lung adenocarcinogenesis
Shiba-Ishii Aya; Hong Jeongmin; Hirokawa Takatsugu; Kim ...
Clinical cancer research : an official journal of the American Association for Cancer Research/25(9)/pp.2809-2820, 2019-02-06 - Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains
Ma Yue; Iida Keisuke; Sasaki Shogo; Hirokawa Takatsug...
Molecules (Basel, Switzerland)/24(2), 2019-01 - The Novel SFN Inhibitors Aprepitant and Ticagrelor Exert Anti-Tumor Effects Through Blocking of Oncoprotein Ubiquitination
Shiba A.; Hong J.; Hirokawa T.; Kim Y.; Noguchil M.
JOURNAL OF THORACIC ONCOLOGY/13(10::S)/pp.S519-S519, 2018-10 - Ligand binding to human prostaglandin E receptor EP at the lipid-bilayer interface
Toyoda Yosuke; Morimoto Kazushi; Suno Ryoji; Horita S...
Nature chemical biology/15(1)/pp.18-26, 2019-01 - Synthesis and biological evaluation of thielocin B1 analogues as protein-protein interaction inhibitors of PAC3 homodimer
Ohsawa Kosuke; Yoshida Masahito; Izumikawa Miho; Takagi ...
Bioorganic & Medicinal Chemistry/26(23-24)/pp.6023-6034, 2018-12 - Development of G-quadruplex ligands for selective induction of a parallel-type topology
Ma Yue; Tsushima Yamato; Sakuma Mai; Sasaki Shogo; Ii...
Organic & biomolecular chemistry/16(40)/pp.7375-7382, 2018-09 - An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
Shuntaro Chiba; Takashi Ishida; Kazuyoshi Ikeda; Masahiro Mo...
Scientific Reports/7, 2017-9 - Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Suno Ryoji; Kimura Kanako Terakado; Nakane Takanori; Y...
Structure (London, England : 1993)/26(1)/pp.7-+, 2017-11 - Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
Okamoto Naoki; Mizote Keisuke; Honda Hiroe; Saeki Aki...
The Journal of biological chemistry/292(37)/pp.15378-15394, 2017-09 - Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock
Shinohara Yuta; Koyama Yohei M; Ukai-Tadenuma Maki; Hi...
Molecular cell/67(5)/p.783-798.e20, 2017-09 - An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
Chiba Shuntaro; Ishida Takashi; Ikeda Kazuyoshi; Mochi...
Scientific reports/7(1), 2017-09 - Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS1 by Docking-Aided Structure-Activity Analysis
Sayama Misa; Inoue Asuka; Nakamura Sho; Jung Sejin; Ikubo...
Journal of medicinal chemistry/60(14)/pp.6384-6399, 2017-07 - BDNF Binds Its Pro-Peptide with High Affinity and the Common Val66Met Polymorphism Attenuates the Interaction
Uegaki Koichi; Kumanogoh Haruko; Mizui Toshiyuki; Hiro...
International journal of molecular sciences/18(5), 2017-05 - Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects
Wada Yasuhiro; Nakano Seiji; Morimoto Akifumi; Kasahara ...
Journal of medicinal chemistry/60(8)/pp.3252-3265, 2017-04 - MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding
Asamitsu Kaori; Hirokawa Takatsugu; Okamoto Takashi
PLOS ONE/12(2), 2017-02 - The Effect of Conformational Flexibility on Binding Free Energy Estimation between Kinases and Their Inhibitors
Araki Mitsugu; Kamiya Narutoshi; Sato Miwa; Nakatsui ...
JOURNAL OF CHEMICAL INFORMATION AND MODELING/56(12)/pp.2445-2456, 2016-12
- Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly