広川 貴次(ヒロカワ タカツグ)

研究者情報全体を表示

論文

• An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
  Chiba Shuntaro; Ishida Takashi; Ikeda Kazuyoshi; Mochi...
  Scientific reports/7(1), 2017-09
  
  PubMed
• Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS1 by Docking-Aided Structure-Activity Analysis
  Sayama Misa; Inoue Asuka; Nakamura Sho; Jung Sejin; Ikubo...
  Journal of medicinal chemistry/60(14)/pp.6384-6399, 2017-07
  
  PubMed
• BDNF Binds Its Pro-Peptide with High Affinity and the Common Val66Met Polymorphism Attenuates the Interaction
  Uegaki Koichi; Kumanogoh Haruko; Mizui Toshiyuki; Hiro...
  International journal of molecular sciences/18(5), 2017-05
  
  PubMed
• Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects
  Wada Yasuhiro; Nakano Seiji; Morimoto Akifumi; Kasahara ...
  Journal of medicinal chemistry/60(8)/pp.3252-3265, 2017-04
  
  PubMed
• MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding
  Asamitsu Kaori; Hirokawa Takatsugu; Okamoto Takashi
  PLOS ONE/12(2), 2017-02
  
  PubMed Tsukuba Repository
• The Effect of Conformational Flexibility on Binding Free Energy Estimation between Kinases and Their Inhibitors
  Araki Mitsugu; Kamiya Narutoshi; Sato Miwa; Nakatsui ...
  JOURNAL OF CHEMICAL INFORMATION AND MODELING/56(12)/pp.2445-2456, 2016-12
  
  PubMed