金子新(カネコシン)

所属

医学医療系

職名

教授

研究分野


内科学一般（含心身医学）
細胞生物学

研究キーワード


遺伝子治療
細胞治療
臨床血液学
幹細胞生物学

研究課題


造血器悪性腫瘍の臨床遺伝子治療	1998 -- (現在)		/

学歴


1989 -- 1995	筑波大学医学専門学群
1998 -- 2002	筑波大学医学研究科血液学・免疫学

取得学位


	博士(医学)	筑波大学

所属学協会


-- (現在)	日本癌学会
-- (現在)	日本がん免疫学会
-- (現在)	日本血液学会
-- (現在)	日本免疫学会
-- (現在)	日本内科学会
-- (現在)	日本免疫治療学会
-- (現在)	日本再生医療学会

受賞


2001	The Young Investigater's award of Japanese Society of Hematology
2001	日本血液学会奨励賞

論文

Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model
KANEKO Shin
Cell Stem Cell, 2024-06
A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism
金子新
Communications biology, 2024-06
ex vivoゲノム編集-HLAゲノム編集を用いた免疫再生治療の実現
金子新; 蟹江慶太郎
実験医学/42(6), 2024-04
Development of B-cell maturation antigen (BCMA)-specific CD8+ cytotoxic T lymphocytes using induced pluripotent stem cell technology for multiple myeloma.
金子新
JOURNAL OF CLINICAL ONCOLOGY/pp.2542-2542, 2022-06
BCR-ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells
Ueda Norihiro; Zhang Rong; Tatsumi Minako; Liu Tian-Y...
Cellular & molecular immunology/15(1)/pp.15-26, 2018-01-01
PubMed
Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors
Oshima Koichi; Saiki Norikazu; Tanaka Michihiro; Imamu...
Biochemical and biophysical research communications/497(2)/pp.719-725, 2018-03-04
PubMed
Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response
Ueda Norihiro; Uemura Yasushi; Zhang Rong; Kitayama S...
Stem cell reports/10(6)/pp.1935-1946, 2018-06-05
PubMed
Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA
Higaki Kei; Hirao Masako; Kawana-Tachikawa Ai; Iriguch...
Molecular therapy. Nucleic acids/12/pp.793-804, 2018-09-07
PubMed
Repurposing the Cord Blood Bank for Haplobanking of HLA-Homozygous iPSCs and Their Usefulness to Multiple Populations
Lee Suji; Huh Ji Young; Turner David M; Lee Soohyeon; ...
Stem cells (Dayton, Ohio)/36(10)/pp.1552-1566, 2018-10-01
PubMed
Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy
Minagawa Atsutaka; Yoshikawa Toshiaki; Yasukawa Masaki...
Cell stem cell/23(6)/p.850-858.e4, 2018-12-06
PubMed
Toward the development of true "off-the-shelf" synthetic T-cell immunotherapy
Iriguchi Shoichi; Kaneko Shin
Cancer science/110(1)/pp.16-22, 2019-01-01
PubMed
Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC
Kawai Yohei; Kaneko Shin
Methods in molecular biology (Clifton, N.J.)/2048/pp.71-75, 2019-04-01
PubMed
In Vitro Differentiation of T Cell: From CAR-Modified T-iPSC
Ueda Tatsuki; Kaneko Shin
Methods in molecular biology (Clifton, N.J.)/2048/pp.85-91, 2019-04-01
PubMed
In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells
Iriguchi Shoichi; Kaneko Shin
Methods in molecular biology (Clifton, N.J.)/2048/pp.93-106, 2019-04-01
PubMed
Differentiating CD8αβ T Cells from TCR-Transduced iPSCs for Cancer Immunotherapy
Minagawa Atsutaka; Kaneko Shin
Methods in molecular biology (Clifton, N.J.)/2048/pp.81-84, 2019-04-01
PubMed
In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
Iriguchi Shoichi; Kaneko Shin
Methods in molecular biology (Clifton, N.J.)/2048/pp.59-70, 2019-04-01
PubMed
In Vitro Detection of Cellular Adjuvant Properties of Human Invariant Natural Killer T Cells
Zhang Rong; Kitayama Shuichi; Liu Tianyi; Ueda Norihi...
Methods in molecular biology (Clifton, N.J.)/2048/pp.121-130, 2019-04-01
PubMed
Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
Xu Huaigeng; Wang Bo; Ono Miyuki; Kagita Akihiro; Fuj...
Cell stem cell/24(4)/p.566-578.e7, 2019-04-04
PubMed
Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis
Radulovic Visnja; van der Garde Mark; Koide Shuhei; Si...
Cell reports/27(10)/p.2826-2836.e5, 2019-06-04
PubMed
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1⁺ Dendritic Cells
Tsuchiya Nobuhiro; Zhang Rong; Iwama Tatsuaki; Ueda N...
Cell reports/29(1)/p.162-175.e9, 2019-10-01
PubMed
Non-clinical efficacy, safety and stable clinical cell processing of induced pluripotent stem cell-derived anti-glypican-3 chimeric antigen receptor-expressing natural killer/innate lymphoid cells
Ueda Tatsuki; Kumagai Ayako; Iriguchi Shoichi; Yasui ...
Cancer science/111(5)/pp.1478-1490, 2020-05-01
PubMed
Podoplanin as an Attractive Target of CAR T Cell Therapy
Waseda Masazumi; Kaneko Shin
Cells/9(9), 2020-08-26
PubMed
Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling
Kazuki Yasuhiro; Uno Narumi; Abe Satoshi; Kajitani Na...
Molecular therapy. Nucleic acids/23/pp.629-639, 2021-03-05
PubMed
Capturing human trophoblast development with naive pluripotent stem cells in vitro
Io Shingo; Kabata Mio; Iemura Yoshiki; Semi Katsunori...
Cell stem cell/28(6)/p.1023-1039.e13, 2021-06-03
PubMed
Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy
Mashima Hiroaki; Zhang Rong; Kobayashi Tsuyoshi; Tsuka...
Molecular therapy. Methods & clinical development/21/pp.171-179, 2021-06-11
PubMed
さらに表示...

担当授業科目


2024-04 -- 2024-08	臨床内科学演習I	筑波大学
2024-10 -- 2025-02	臨床内科学演習II	筑波大学
2024-04 -- 2024-08	臨床内科学実験実習I	筑波大学
2024-10 -- 2025-02	臨床内科学特論II	筑波大学
2024-04 -- 2024-08	臨床内科学特論I	筑波大学
2024-10 -- 2025-02	臨床内科学実験実習II	筑波大学
2023-04 -- 2023-08	臨床内科学演習I	筑波大学
2023-10 -- 2024-02	臨床内科学実験実習II	筑波大学
2023-04 -- 2023-08	臨床内科学特論I	筑波大学
2023-10 -- 2024-02	臨床内科学特論II	筑波大学
さらに表示...

一般講演

遺伝子改変による高機能型iPS由来CAR-T（予定）
金子新
第22回日本再生医療学会総会/2023-03-25
がん治療のための iPS 細胞由来免疫細胞の製造と臨床試験
金子新
再生医療実現拠点ネットワークプログラム　iPS細胞研究中核拠点　第5回情報交換会/2023-02-15
アロジェニックCAR-T
金子新
第7回再生医療産官学連携シンポジウム/2023-01-26
免疫再生研究と産業化への取り組み
金子新
再生医療を推進する議員の会/2022-12-15
DEVELOPMENT OF IPSC-DERIVED FUNCTIONAL LYMPHOCYTES FOR IMMUNE CELL THERAPY
Kaneko Shin
2022 Symposium on Cell Manufacturing and Commercialization/2022-11-19
iPS細胞からのT細胞再生と同種CAR-T療法、TCR-T療法の開発
金子新
第84回日本血液学会学術集会/2022-10-15
iPS細胞を用いたがん免疫再生療法の研究
金子新
メディア勉強会/2022-09-15
CD8 killer T cells and NK cells from iPSC for cancer immunotherapy
金子新
第28回日本遺伝子細胞治療学会学術集会/2022-07-16
iPS cell-based technologies for allogeneic cancer immunotherapy
Kaneko Shin
The 1st Catholic International Symposium for Advenced Regenerative Medicine/2022-07-08
iPS由来T細胞、NK細胞を用いた新たながん治療～基礎から最前線まで
金子新
SBI証券講演会/2022-06-24
Development of CAR-T cell therapy using allogeneic induced pluripotent stem cells
Kaneko Shin
ISSCR: Workshop Clinical Translation/2022-06-15
Induced pluripotent stem cell derived killer cell for CAR-based cancer immunotherapy
Kaneko Shin
Mayo Clinic Honorarium Lecture/2022-06-11
iPS細胞から誘導したCD8キラーT細胞とNK細胞の特性
金子新
第19回日本免疫治療学会学術集会/2022-05-22
iPS細胞を用いた免疫再生治療の開発
金子新
第1回EPU先端医療セミナー/2022-05-20
iPS細胞からのキラーT細胞、NK細胞の再生と臨床応用
金子新
第44回日本造血・免疫細胞療法学会総会/2022-05-13
Development of iPSC-derived Immune Cells For Cancer Immunotherapy
Kaneko Shin
ISCT 2022/2022-05-05

(最終更新日: 2024-10-30)

金子 新(カネコ シン)

金子新(カネコシン)