HO Kiong(ホー キョン)
- 所属
- 医学医療系
- 職名
- 准教授
- URL
- eメール
- +@>DC<=DXgcB9aIHJ@J76a68a?En
- 研究分野
- 寄生虫学(含衛生動物学) - 機能生物化学 - 分子生物学 
- 研究キーワード
- Parasitology, RNA Processing, RNA ligation, Trypanosoma 
- 研究課題
- Structure and biological targets of Trypanosome mRNA recapping enzyme - 2021 -- 2023 - HO KIONG - 日本学術振興会/基盤研究(C) - 4,290,000円 - Mechanism of mRNA recapping pathway in trypanosome - 2016-04 -- 2020-03 - HO Kiong - 日本学術振興会/科研費/基盤研究(B) - 17,290,000円 - Structural, Functional and Genetic Analysis of Archaea RNA Ligase - 2011-04 -- 2016-03 - Kiong Ho - アメリカ国立科学財団/Div Of Molecular and Cellular Bioscience - 76,500,000円 - Mechanism of mRNA cap formation in Trypanosoma brucei - 2006-07 -- 2011-06 - HO KIONG - アメリカ心臓協会/Scientist Development Grant - 26,000,000円 - Mechanism of Archaeal RNA ligase - 2007-07 -- 2008-09 - HO KIONG - University at Buffalo/UB2020 Interdisciplinary Research Development Fund - 4,000,000円 
- 職歴
- 2003-01 -- 2010-10 - ニューヨーク州立大学、バッファロー校Department of Biological Sciences助教授 - 2000-01 -- 2003-10 - スローンケタリンがん研究所Program in Molecular Biology主任研究員 - 1997-04 -- 1999-12 - スローンケタリンがん研究所(米国)Program in Molecular BiologyPost-doctoral Fellow 
- 学歴
- 1986-09 -- 1990-01 - 米国ラトガース大学 ニュージャージー州立大学 College of Arts and Sciences 生物化学 - 1990-09 -- 1997-03 - 米国コーネル大学医科学大学院 分子生物 Ph.D. 分子生物 
- 取得学位
- 1997-02 - Ph.D. Molecular Biology - 米国コーネル大学医科学大学院 - 1990-1 - Bachelor of Arts, Biochemistry - ラトガーズ、ニュージャージ州立大学 
- 所属学協会
- 2020-01 -- 2020-12 - American Society for Biochemistry and Molecular Biology - 1997-01 -- 2020-12 - ASM (American Society of Microbiology) - 2017-04 -- (現在) - 日本寄生虫学会 - 2007-01 -- 2020-03 - RNA Society (International) - 2017-04 -- (現在) - 日本RNA学会 
- 受賞
- 2024-03 - 医学学群長賞 
- 論文
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
 Ignatochkina Anna V; Iguchi Jesavel A; Kore Anilkumar ...
 Nucleic Acids Research/Epub, 2024-07
- Factors Affecting Undergraduate Medical Science Students’ Motivation to Study during the COVID-19 Pandemic
 Mayers Thomas David; Mathis Bryan J.; Ho C. Kiong; Morika...
 Education Sciences/12(9), 2022-09
- Editorial: mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation
 Kiss L. Daniel; Vasudevan Deepika; Ho Kiong; Caliskan Neva
 FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-06
- Genetic and functional analyses of archaeal ATP-dependent RNA ligase in C/D box sRNA circularization and ribosomal RNA processing
 Liu Yancheng; Takagi Yuko; Sugijanto Milyadi; Nguyen Kie...
 FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-03
- The impact of the COVID-19 pandemic on medical science students’ motivation to study: Preliminary findings
 Mayers Thomas David; Mathis Bryan J; Ho Kiong; Morikawa ...
 Journal of Medical English Education./20(3)/pp.52-55, 2021-10
- An essential surface motif (WAQKW) of yeast RNA triphosphatase mediates formation of the mRNA capping enzyme complex with RNA guanylyltransferase
 Ho Kiong; Lehman Kevin; Shuman Stewart
 Nucleic Acids Research/27(24)/pp.4671-4678, 1999-01
- Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills
 Ho C. Kiong; Mayers Thomas David; Morikawa Kazuya; Watana...
 Journal of Medical English Education/20(3)/pp.39-46, 2021-10
- Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
 Mayers Thomas; Morikawa Kazuya; Fukuda Aya; Watanabe Yuk...
 J Med Eng Educ/19(1)/pp.40-44, 2020-02
- Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5' end of the RNA substrate
 Takagi Yuko; Kuwabara Naoyuki; Dang Truong Tat; Furukawa ...
 Journal of Biological Chemistry/295(27)/pp.9076-9086, 2020-05
- Mutational Analyses of Yeast RNA Triphosphatases Highlight a Common Mechanism of Metal-dependent NTP Hydrolysis and a Means of Targeting Enzymes to Pre-mRNAs in Vivo by Fusion to the Guanylyltransferase Component of the Capping Apparatus
 Pei Yi; Ho Kiong; Schwer Beate; Shuman Stewart
 Journal of Biological Chemistry/274(41)/pp.28865-28874, 1999-10
- An international exchange program for undergraduate medical science students.
 Mayers Thomas; Morikawa Kazuya; Ho Kiong; Ohneda Osamu
 J Med Eng Educ/17(1)/pp.7-13, 2018-04
- Cleavage of 3'-terminal adenosine by archaeal ATP-dependent RNA ligase
 Yoshinari Shigeo; Liu Yancheng; Gollnick Paul; Ho C Kiong
 Scientific reports/7(1), 2017-09
- Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis
 Gu H; Yoshionari S; Ghosh R; Ignatochkina AV; Gollnick PD; Mur...
 Nucleic acids research/44(5)/pp.2337-2347, 2016-03
- Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase
 Paul Smith; Ho Kiong; Yuko Takagi; Hakim Djaballah; Stewart S...
 mBIO/7(1)/p.10.1128/mBio.00058-16, 2016-02
- Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
 Ho Kiong
 The Journal of Medical English Education/14(3)/pp.93-98, 2015-10
- The messenger RNA decapping and recapping pathway in Trypanosoma
 Ignatochkina AV; Takagi Y; Liu Y; Negate K; Ho Kiong
 Proceedings of the National Academy of Sciences USA/112(22)/pp.6967-6972, 2015-06
- Archaea RNA Ligase is a Homodimeric Protein that Catalyzes Intramolecular Ligation of Single-Stranded RNA and DNA.
 Torchea C Takagi Y and Ho CK.
 Nucleic Acid Research/36/p.6218-6227, 2008-01
- Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events.
 Dong H; Ray D; Ren S; Zhang B; Puig-Basagoiti F; Takagi ...
 J. Virol./81/p.4412-4421, 2007-01
- Trypanosoma brucei Encodes a Bifunctional Capping Enzyme Essential for Cap 4 Formation on the Spliced Leader RNA.
 Takagi Y Sindkar S Ekonomidis D Hall MP and Ho CK.
 J. Biol. Chem/282/p.15995-16005, 2007-01
- Characterization of a Trypanosoma brucei mRNA Cap (Guanine N-7) Methyltransferase.
 Hall MP and Ho CK.
 RNA/12/p.488 -497, 2006-01
- Functional Characterization of a 48-kDa Trypanosoma brucei Cap 2 RNA Methyltransferase.
 Hall MP and Ho CK.
 Nucleic Acid Research/34/p.5594 - 5602, 2006-01
- Identification of the MicroRNAs of the Herpesvirus Family.
 Pfeffer S Sewer A Lagos-Quintana M Sheridan R Sander...
 Nature Method/2/p.269-276, 2005-01
- Structure and Mechanism of RNA Ligase.
 Ho CK Wang LK Lima CD and Shuman S.
 Structure/12/p.327-339, 2004-01
- Portability and Fidelity of RNA Repair Systems.
 Schwer B; Sawaya R; Ho CK; Shuman S.; +HO KIONG
 Proc. Natl. Acad. Sci. USA/101/p.2788-2793, 2004-01
- Characterization of Bacteriophage KVP40 and T4 RNA Ligase 2.
 Yin S Ho CK Miller ES and Shuman S.
 Virology/319/p.141-151, 2004-01
- さらに表示...
 
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
- 著書
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
 Ho Kiong
 Methods Molecular Biology/Humana Press, New York, NY/pp.1-9, 2017-08
 
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
- 会議発表等
- RNA Methylation Controls mRNA Recapping to Regulate Gene Expression in Protozoan Parasites
 HO Kiong
 Workshop in Biomedical Materials and Technologies/2025-03-03--2025-03-05
- 4th University of Tsukuba-VMU University of Science Symposium in Biomedical Science
 HO Kiong
 Symposium in Biomedical Science/2025-03-01--2025-03-01
- Identification of Biological Targets of Cytoplasmic Capping Enzymes in Trypanosoma
 Nguyen Kieu DM; HO Kiong
 2024 Tsukuba Global Science Week/2024-09-30--2024-10-4
- Identification of biological targets of the cytoplasmic capping enzyme in Trypanosoma cruzi
 Nguyen Kieu DM; Takagi Yuko; HO Kiong
 Biomolecular Horizons 2024/2024-09-22--2024-09-26
- Identification of Cytoplasmic mRNA Capping Targets in Trypanosoma cruzi
 HO Kiong
 第93回日本寄生虫学会大会/2024-03-09--2024-03-10
- Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
 HO Kiong; Ignatochikina Anna; Akichika Shinichiro; Suz...
 第24回日本RNA学会/2023-07-03--2023-07-05
- The Analysis of Uncapped mRNA Transcriptome in Trypanosoma Parasites
 Nguyen Kieu DM; Takagi Yuko; HO Kiong
 第24回日本RNA学会年会/2023-07-05--2023-07-07
- University of Tsukuba Joint Symposium in Biomedical Science
 Ho Kiong
 The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18
- The Identification and Characterization of RNA Recapping Targets in Trypanosomes
 Ho Kiong
 The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18
- Unique Cap-dependent RNA Methyltransferase activity in Trypanosoma brucei
 Ho Kiong
 第23回日本RNA学会年会/2022-07-20--2022-07-22
- Circularization of C/D Box sRNA by Archaeal ATP-Dependent RNA Ligase.
 Ho Kiong
 第23回日本RNA学会年会/2022-07-20--2022-07-22
- Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
 Ho Kiong
 第92回日本寄生虫学会大会/2023-03-30--2023-03-31
- Medical science summer research program in the University of Tsukuba in the era of COVID-19
 Mayers Thomas David; Ho C. Kiong
 第 55 回日本医学教育学会大会/2023-07-28--2023-07-29
- The impact of the COVID-19 pandemic on medical science students’ motivation to study
 Mayers Thomas David; Mathis Bryan James; Ho C. Kiong; Mor...
 日本医学英語教育学会学術集会/2021-07-17--2021-07-18
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
 Ho Kiong; Anna Ignatochkina
 第3回つくば精製フォーラム/2021-02-19--2021-02-19
- Regulation of Protozoa Gene Expression  by mRNA Recapping Pathway
 Ho Kiong
 The 2nd Joint Young Researcher Meeting in Biomedical Sciences/2020-01-10--2020-01-11
- トリパノソーマRNA triphosphataseの結晶構造解析による三リン酸ならびに核酸認識機構の解明
 Ho Kiong; Takagi Yuko; Kuwabara Naoyuki; Truong Dang; Fur...
 第42回日本分子生物学会/2019-12-03--2019-12-06
- Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
 Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
 第22回日本医学英語教育学会学術集会/2019-08-03--2019-08-04
- Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
 Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
 第22回日本医学英語教育学会学術集会/2019-08-03--2019-08-04
- Targeting of mRNA Cap Formation for Treatment of Parasitic Infections
 Ho Kiong
 The Joint Symposium in Infectious Diseases/2019-02-22--2019-02-22
- Structural and Functional Analysis of protozoan mRNA capping enzyme
 HO KIONG
 第20回日本RNA学会年会/2018-07-09--2018-07-12
- The messenger RNA recapping pathway in Trypanosome
 Ho Kiong
 第88回日本寄生虫学会大会/2019-03-14--2019-03-16
- Structural and Functional Analysis of Trypanosoma RNA Triphosphatase
 HO KIONG
 第88回日本寄生虫学会大会/2019-03-14--2019-03-16
- RNA methylation at the 5’-end of the mRNA stimulates Trypanosoma mRNA recapping activities
 Ho Kiong
 Cold Spring Harbor Meeting, Translational Control Meeting/2018-09-04--2018-09-08
- Structure and mechanism of archaeal ATP-dependent RNA ligase
 Ho Kiong; Yoshinari Shigeo; Murakami Katsuhiko S.
 Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17
- さらに表示...
 
- RNA Methylation Controls mRNA Recapping to Regulate Gene Expression in Protozoan Parasites
- 担当授業科目
- 2026-01 -- 2026-02 - 専門語学(英語)P - 筑波大学 - 2025-10 -- 2026-02 - 国際実践医科学研究特論III - 筑波大学 - 2025-04 -- 2025-08 - 国際実践医科学研究特論III - 筑波大学 - 2025-10 -- 2026-02 - 国際実践医科学研究特論II - 筑波大学 - 2025-04 -- 2025-08 - 国際実践医科学研究特論II - 筑波大学 - 2025-10 -- 2026-02 - 国際実践医科学研究特論I - 筑波大学 - 2025-04 -- 2025-08 - 国際実践医科学研究特論I - 筑波大学 - 2026-01 -- 2026-02 - 健幸医科学グループワーク - 筑波大学 - 2025-04 -- 2025-06 - 基礎医学総論 - 筑波大学 - 2025-10 -- 2026-02 - 感染症医科学演習 - 筑波大学 - さらに表示... 
- 授業以外の教育活動
- 2024-10 -- 2024-10 - Summer Research Program Plus 2024 - 筑波大学 - 2024-07 -- 2024-07 - Summer Research Program Online 2024 - 筑波大学医学医療系 - 2025-02 -- 2025-02 - Undergraduate Medical Science Course in Tsukuba - 筑波大学医療科学 - 2024-08 -- 2024-08 - 感染生物ワークショップ - HCMC Biotechnology Center, Vietnam - 2023-08 -- 2023-08 - 感染生物ワークショップ - VNU International University (HCMC), Vietnam - 2023-08 -- 2023-08 - Undergraduate Medical Science Course in Tsukuba - 筑波大学 - 2023-07 -- 2023-07 - Summer Research Program Online 2023 - 筑波大学医学医療系 - 2023-10 -- 2023-10 - Summer Research Program Plus 2023 - 筑波大学医学医療系 - 2021-06 -- 2023-06 - Frontiers in Molecular Biosciences - 2022-02 -- 2022-02 - 感染生物ワークショップ - さらに表示... 
- 一般講演
- RNA Methylation Controls mRNA Recapping to Regulate Gene Expression in Protozoan Parasites
 HO Kiong
 Research Seminar Series at VNU International Univeristy/2025-03-03--2025-03-03
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
 Ho Kiong; Anna Ignatochkina
 第3回つくば精製フォーラム/2021-02-19--2021-02-19
- Structure and Mechanism of RNA Repair Enzymes
 Ho Kiong
 生命と機能とかたち/2018-03-07--2018-03-07
 
- RNA Methylation Controls mRNA Recapping to Regulate Gene Expression in Protozoan Parasites
- 学内管理運営業績
- 2018-04 -- (現在) - 全学 学群教育課程委員会 - 委員 - 2021-04 -- 2023-04 - 全学 留学生後援会基金運営委員会 - 委員 - 2020-04 -- (現在) - 全学 国際交流支援室企画・審査委員会 - 委員 - 2020-04 -- (現在) - 全学 海外生教育プログラム等検討委員会 - 委員 - 2018-04 -- (現在) - 全学 国際戦略委員会 - 委員 - 2021-04 -- (現在) - 医学医療系 国際連携委員会 - 委員長 - 2018-04 -- 2020-03 - 医学医療系 国際連携委員会 - 副委員長 - 2021-04 -- (現在) - 医学医療系 企画委員会 - 委員 - 2019-04 -- (現在) - ヒューマンバイオロジープログラム 学位審査委員会 - 委員長 - 2016-04 -- 2018-03 - ヒューマンバイオロジープログラム 学位審査委員会 - 委員 - さらに表示... 
- その他の活動
- 2021-04 -- (現在) - Frontiers in Molecular Bioscience - Associate Editor 
(最終更新日: 2025-08-19)