Nabekura Tsukasa
- Affiliation
- Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
- Official title
- Assistant Professor
- Sex
- Male
- Birth date
- 1981-01
- KAKEN ID
- 80550095
- URL
- G'xy|$.+xE-,.$x,xE}|<KG.E-,.$.yxExzE#)
- Phone
- +81-29-853-3281
- Research fields
Immunology - Research keywords
Natural killer cells Immunological memory Viral infection Innate lymphoid cells Immunology Tumor immunology Bone marrow transplant Hematology - Research projects
記憶NK細胞の人為的分化誘導法 の開発とその応用 2022-04 -- 2024-03 鍋倉宰 科学技術振興機構(JST)/創発的研究支援事業 26,000,000Yen 記憶ナチュラルキラー細胞分化の制御機構の解明とその応用 2021-04 -- 2022-03 鍋倉宰 国立大学法人筑波大学/研究力強化のための令和3年度特別支援シーディングプログラム 10,000,000Yen JSI 2020 Outstanding Young Immunology Researcher Award 2021-01 -- 2021-12 鍋倉宰 特定非営利活動法人日本免疫学会/若手免疫学研究支援事業 ナチュラルキラー細胞の適応免疫特性獲得の制御機構の研究 2020-04 -- 2021-03 鍋倉宰 国立大学法人筑波大学/令和2年度第1回 筑波大学研究基盤支援プログラム(Bタイプ) 2,700,000Yen 急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割 2018-04 -- 2021-03 鍋倉宰 The Naito Foundation/The Naito Grant for Fostering Scientific Full Bloom for the Next Generation 6,000,000Yen 急性肝障害におけるDNAM-1の役割 2018-04 -- 2020-03 鍋倉宰 Kato Memorial Bioscience Foundation/Grant-in-Aid 2,000,000Yen 急性肝障害におけるDNAM-1の役割 2018-04 -- 2019-03 鍋倉宰 Life Science Foundation of Japan/Grant-in-Aid 1,000,000Yen 急性肝障害におけるDNAM-1 の役割 2018-04 -- 2019-03 鍋倉宰 The Uehara Memorial Foundation/Grant-in-Aid 2,000,000Yen 急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割 2018-04 -- 2019-03 鍋倉宰 Kanae Foundation for the Promotion of Medical Science/The 46th Kanae grant 1,000,000Yen Identification of a master regulator of the differentiation of memory natural killer cells 2017-04 -- 2020-03 鍋倉宰 Japan Society for the Promotion of Science/Grant-in-Aid for Young Scientists(A) 24,310,000Yen more... - Career history
2018-04 -- (current) University of TsukubaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)Assistant Professor 2014-03 -- 2018-03 University of TsukubaLife Science Center of Tsukuba Advanced Research Alliance (TARA)International Tenure-track Assistant Professor 2014-11 -- 2016-10 University of California, San FranciscoDepartment of Microbiology and Immunology, Lewis L. Lanier labAssistant Specialist 2011-11 -- 2014-10 University of California, San FranciscoDepartment of Microbiology and Immunology, Lewis L. Lanier labPostdoctoral Scholar 2008-04 -- 2011-10 University of TsukubaGraduate School of Comprehensive Human SciencesPostdoctoral fellow - Academic background
2005-04 -- 2008-03 University of Tsukuba Graduate School of Comprehensive Human Sciences Doctoral Program in Advanced Biomedical Applications - Degree
2008-03 Ph.D. University of Tsukuba - Academic societies
2017 -- (current) Japanese Society of Immunotherapy for Hematological Disorders 2012 -- 2016 The American Association of Immunologist (AAI) 2009 -- 2010 THE JAPANESE SOCIETY OF HEMATOLOGY 2003 -- (current) JAPANESE SOCIETY FOR IMMUNOLOGY - Honors & Awards
2018-11 Young Investigator Award in University of Tsukuba 2018-02 BEST FACULTY MEMBER in University of Tsukuba 2017-12 The Japanese Society of Immunology Young Investigator Award 2013-05 AAI Trainee Abstract Award of IMMUNOLOGY 2013 Annual Meeting, The American Association of Immunologists 2012-11 Postdoctoral Fellowship for Research Abroad of the Japan Society for the Promotion of Science (JSPS) 2011-11 Postdoctoral Fellowship of the Uehara Memorial Foundation 2011-11 Subsidy for Inter-Institute Researches of the Naito Foundation 2011-11 Fellowship for Research Abroad of the Mochida Memorial Foundation for Medical and Pharmaceutical Research 2011-01 Most Valuable Presenter in the 5th Tsukuba Medical Science Research Meeting 2011-01 Best Paper Award in the 5th Tsukuba Medical Science Research Meeting 2008-04 Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), PD 2008-03 Graduate with Summa Cum Laude (3-year graduation in 4-year Doctoral Course), University of Tsukuba 2007-04 Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), DC2 2006-01 Cancer Research Fellowship for Graduate Students of Yasuda Medical Foundation 2005-03 Best Paper Award in the Master’s Program in Medical Sciences, University of Tsukuba 2005-03 Graduate with Summa Cum Laude (Best Paper Award in Master Course), University of Tsukuba 2003-03 Graduate with Summa Cum Laude (Undergraduate Course), University of Tsukuba - Articles
- DNAM-1 immunoreceptor protects mice from concanavalin A-induced acute liver injury by reducing neutrophil infiltration
Matsuo Soichi; Nabekura Tsukasa; Matsuda Kenshiro; Shibuy...
Journal of Immunology/211(6)/pp.954-963, 2023-09 - Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches
Asahi Takuma; Abe Shinya; Cui Guangwei; Shimba Akihiro; N...
Elife/12/p.e84209, 2023-06 - The CD16 and CD32b Fc-gamma receptors regulate antibody-mediated responses in mouse natural killer cells
Aguilar Oscar A; Gonzalez-Hinojosa Maria D R; Arakawa-H...
JOURNAL OF LEUKOCYTE BIOLOGY/113(1)/pp.27-40, 2023-01-10 - Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming
Aizawa Shiho; Nishimura Ken; Mondejar Gonzalo Seminario; ...
Stem Cell Reports/17(1)/pp.53-67, 2022-01 - 急性肝障害とILC1
松尾 壯一; 鍋倉 宰; 渋谷 彰
臨床免疫・アレルギー科/76/pp.581-586, 2021 - 1型自然リンパ球が急性肝障害において、保護的な役割を持つ
鍋倉 宰; 渋谷彰
感染・炎症・免疫/51(2)/pp.54-55, 2021 - Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells
Iijima Ayana; Kanemaru Kazumasa; Wang Yaqiu; Nabekura Ts...
Biochemical and Biophysical Research Communications/561/pp.101-105, 2021-05 - 1型自然リンパ球は急性肝障害において保護的な役割を持つ
鍋倉 宰; 渋谷彰
医学のあゆみ/276/pp.730-731, 2021 - ILC1: guardians of the oral mucosa against enemy viruses
Nabekura Tsukasa; Shibuya Akira
Immunity/54(2)/pp.196-198, 2021-02 - Type 1 innate lymphoid cells: Soldiers at the front line of immunity
Nabekura Tsukasa; Shibuya Akira
Biomedical Journal/44(2)/pp.115-122, 2021 - Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes
Nabekura Tsukasa; Riggan Luke; Hildreth Andrew D.; O’Sull...
IMMUNITY/52(1)/pp.96-108, 2020-01 - The cis-Regulatory Atlas of the Mouse Immune System
Yoshida Hideyuki; Lareau Caleb A; Ramirez Ricardo N; Rose...
Cell/176(4)/p.897-912.e20, 2019 - Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection
Nabekura Tsukasa; Chen Zhiying; Schroeder Casey; Park Ta...
Journal of Immunology/200(10)/pp.3420-3428, 2018 - Cutting Edge: NKG2D Signaling Enhances NK Cell Responses but Alone Is Insufficient To Drive Expansion during Mouse Cytomegalovirus Infection
Nabekura Tsukasa; Gotthardt Dagmar; Niizuma Kouta; Trs...
JOURNAL OF IMMUNOLOGY/199(5)/pp.1567-1571, 2017-09 - Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets
Robinette ML Fuchs A Cortez VS Lee JS Wang Y Durum S...
Natuire Immunology/16/p.306, 2015 - Expression profiling of constitutive mast cells reveals a unique identity within the immune system
Dwyer DF Barrett NA Austen KF Kim EY Brenner MB Shaw...
Nature Immunology/17/p.878, 2016 - DNAM-1分子によるNK細胞の活性化
Nabekura Tsukasa; 渋谷和子; 渋谷彰
臨床免疫・アレルギー科/51/p.471, 2010 - ナチュラルキラー細胞
Nabekura Tsukasa; 渋谷和子; 渋谷彰
侵襲と免疫/19/p.17, 2010 - サイトメガロウイルス感染におけるナチュラルキラー細胞の役割
Nabekura Tsukasa
臨床免疫・アレルギー科/64/p.526, 2015 - Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
Nabekura Tsukasa; Lanier Lewis L.
JOURNAL OF EXPERIMENTAL MEDICINE/213(12)/pp.2745-2758, 2016-11 - Activating Receptors for Self-MHC Class I Enhance Effector Functions and Memory Differentiation of NK Cells during Mouse Cytomegalovirus Infection
Nabekura Tsukasa; Lanier Lewis L.
IMMUNITY/45(1)/pp.74-82, 2016-07 - Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice
Tsukasa Nabekura; Kazuko Shibuya; Eri Takenaka; Hirayasu ...
Proc Natl Acad Sci, USA, 2010-10 - IL-33 Receptor ST2 Amplifies the Expansion of NK Cells and Enhances Host Defense during Mouse Cytomegalovirus Infection
Nabekura Tsukasa; Girard Jean-Philippe; Lanier Lewis L.
JOURNAL OF IMMUNOLOGY/194(12)/pp.5948-5952, 2015-06 - Antigen-specific expansion and differentiation of natural killer cells by alloantigen stimulation
Nabekura Tsukasa; Lanier Lewis L.
JOURNAL OF EXPERIMENTAL MEDICINE/211(12)/pp.2455-2465, 2014-11 - Increased CD11b+ Gr-1+ cell population in the placenta after infection with Toxoplasma gondii
Takeshima K; Sato K; Nabekura T; Nagamune K; Hamada H; Yo...
MICROBIOLOGY AND IMMUNOLOGY/59(2)/pp.95-98, 2015-02 - more...
- DNAM-1 immunoreceptor protects mice from concanavalin A-induced acute liver injury by reducing neutrophil infiltration
- Books
- An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2
Nabekura Tsukasa
2008-03
- An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2
- Conference, etc.
- Identification of a functional ligand for Clec10a involved in TLR4-Mediated Skin Inflammation
重松克伸; 鍋倉宰; 田原聡子; 金丸和正; 浩章 舘野; Shibuya Kazuko; 澁谷彰
The 13th JSH International Symposium 2023/2023-7-21 - 記憶NK細胞の分化制御因子Themis2の同定
鍋倉 宰
University of Tsukuba 50th anniversary TARA symposium/2023-06 - Regulation of natural killer memory
鍋倉 宰
The 6th Japanese Society of Immunology Young Academy Seminar/2023-01 - The scaffold protein Themis2 limits natural killer memory formation during mouse cytomegalovirus infection
Nabekura Tsukasa
International Symposium on Immune Regulation/2023-01 - Future direction (young investigators’ forum: Future of Immunology)
鍋倉 宰
The 51st Annual Meeting of Japanese Society of Immunology/2022-12 - 記憶NK細胞の人為的分化誘導法の開発とその応用
鍋倉 宰
科学技術振興機構 創発的研究支援事業 第1回「融合の場」/2022-06 - 記憶NK細胞の人為的分化誘導法の開発とその応用
鍋倉 宰
科学技術振興機構 創発的研究支援事業 第2回「創発の場」/2022-03 - Adaptive immune features of natural killer cells (afternoon seminar)
鍋倉 宰
The 50th Annual Meeting of the Japanese Society of Immunology/2021-12 - Protective role of type 1 innate lymphoid cells in acute liver injury (symposium)
Nabekura Tsukasa
The 50th Annual Meeting of the Japanese Society of Immunology/2021-12 - Recent advances in innate lymphocyte research (overview talk)
Nabekura Tsukasa
The 50th Annual Meeting of the Japanese Society of Immunology/2021-12 - 1型自然リンパ球は急性肝障害において保護的な役割を持つ
鍋倉 宰
第8回筑波大学・東京理科大学合同リトリート/2020-11-14 - Protective role of type 1 innate lymphoid cells in acute liver injury
鍋倉 宰
第29回東京免疫フォーラム/2021-03 - Protective role of type 1 innate lymphoid cells in acute liver injury
Nabekura Tsukasa
The 48th Annual Meeting of the Japanese Society of Immunology/2019-12 - Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus Infection
Nabekura Tsukasa
The 3rd International Conference of Innate Lymphoid Cel/2018-11 - Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
Nabekura Tsukasa
RIKEN Center for Integrative Medical Sciences (IMS) – Japanese Society of Immunology (JSI) International Symposium on Immunology 2018/2018-06 - 活性化受容体NKG2D はマウスサイトメガロウイルス感染時のナチュラルキラー細胞の増殖を促進するが、NKG2D シグナル単独では増殖に不十分である
鍋倉 宰
第6回筑波大学・東京理科大学合同リトリート/2018-03-17 - Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
Nabekura Tsukasa
The 46th Annual Meeting of the Japanese Society of Immunology/2017-12 - 共刺激分子DNAM-1はサイトメガロウイルス感染時に於ける記憶ナチュラルキラー分化に必要である
鍋倉 宰; 金谷 穣; 渋谷 彰; Guo Fu; Gascoigne Nicholas R.J; Lanier Le...
第9回血液疾患・免疫療法学会学術集会/2017-09-30 - 自己MHCクラスIを認識する活性化NK細胞受容体はNK細胞のエフェクター機能と記憶細胞分化を促進する
鍋倉 宰
第9回血液・疾患免疫療法学会学術集会/2017-09-30 - Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection
Nabekura Tsukasa
第26回東京免疫フォーラム/2017-03 - Natural killer cell licensing and tolerance modulate differentiation of natural killer cells during mouse cytomegalovirus infection
Nabekura Tsukasa
The 44th Annual Meeting of the Japanese Society of Immunology/2015-11 - DNAM-1 is required for expansion of effector NK cells and generation of memory NK cells during mouse cytomegalovirus infection
Nabekura Tsukasa
IMMUNOLOGY 2013 AAI Annual Meeting at Honolulu/2013-05 - 活性化免疫受容体DNAM-1の急性肝GVHDの病態形成における重要な役割
金谷 穣; 渋谷 和子; 阿部 史枝; 鍋倉 宰; 渋谷 彰
第4回造血器腫瘍免疫療法研究会学術集会/2012-08-18 - The role of CD155, a novel co-stimulatory molecule in CD4+ T cells, in contact dermatitis
Yumi Kanemaru; Yuichi Takahashi; Yinan Wang; Aya Yoshioka; Ts...
第40回 日本免疫学会総会・学術集会/2011-11 - A critical role of DNAM-1 in the development of acute graft-versus-host disease
Nabekura Tsukasa
The 5th Tsukuba Medical Science Research Meeting/2011-01 - more...
- Identification of a functional ligand for Clec10a involved in TLR4-Mediated Skin Inflammation
- Intellectural property rights
- ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
渋谷 彰; 小田 ちぐさ; 田原 聡子; Nabekura Tsukasa; カンカーナム ガマゲ サナトゥ ウダヤンガ... - NKp46-CreERT2 transgenic mice
Nabekura Tsukasa; Lanier L Lewis - 活性調節剤、これを含有する医薬品、および抗CD300a抗体
渋谷 彰; 小田 ちぐさ; 田原 聡子; 鍋倉 宰; カンカーナム ガマゲ サナトゥ ウダヤンガ; 三木 春香; 飯野 秀一 - Use of Celiac disease-associated CD300a gene-deficient mouse, activity modulator for CD300a-expressing cells, and medical and pharmaceutical agent comprising activity modulators for CD300a-expressing cells
渋谷 彰; 小田 ちぐさ; 鍋倉 宰 - A Method for Generation of Antibodies Using Genetically Modified Dendritic Cells by Vectors
小野寺 雅史; 大津 真; 鍋倉 宰 - Adoptive Gene and Cell Therapy with Immune Cells Genetically Modified by Retroviral Vectors
小野寺 雅史; 濱仲 早苗; 鍋倉 宰; 中内 啓光 - ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
渋谷 彰; 小田 ちぐさ; 田原 聡子; 鍋倉 宰; カンカーナム ガマゲ サナトゥ ウダヤンガ; 三木 春香; 飯野 秀一
- ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
- Teaching
2024 -- 2024 医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年) 筑波大学 2023 -- 2023 Human Infection and Immunology University of Tsukuba. 2023 -- 2023 Immunobiology University of Tsukuba. 2023 -- 2023 Practice of Immunology University of Tsukuba. 2023 -- 2023 医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年) 筑波大学 2022 -- 2022 Early Career Immunology Digital Seminar Series 2022 University of California, Los Angeles 2022 -- 2022 免疫生物学(科目番号:EB91271・夏・集中) 筑波大学 2022 -- 2022 ヒトの感染と免疫(Human Infection and Immunology)(科目番号:01EQ131・春・AB) 筑波大学 2022 -- 2022 免疫検査学実習(科目番号:HE33053・春・集中) 筑波大学 2021 -- 2021 医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年) 筑波大学 more... - Other educational activities
2019 -- 2023 教員抜擢昇任人事制度「ツクバ・トップ・ランナー」教員 2018 -- 2018 筑波大学大学院 博士課程教育リーディングプログラム ヒューマンバイオロジー学位プログラム イニシャルメンター教員 筑波大学 2018 -- (current) 筑波大学大学院 博士課程教育リーディングプログラム ヒューマンバイオロジー学位プログラム 担当教員資格認定 筑波大学 2017 -- (current) 筑波大学大学院 人間総合科学研究科博士課程 生命システム医学専攻 担当教員資格認定 筑波大学 2017 -- (current) 筑波大学大学院 人間総合科学研究科修士課程 フロンティア医科学専攻 担当教員資格認定 筑波大学 - Professional activities
2023-04 -- 2024-03 The 10th Retreat of Univ. of Tsukuba and Tokyo Univ. of Science Program committee member 2022-04 -- 2023-03 The 9th Retreat of Univ. of Tsukuba and Tokyo Univ. of Science Management Secretariat 2020-04 -- (current) The Japanese Society for Immunology Committee member of young academy 2019-04 -- 2020-03 The 8th Retreat of Univ. of Tsukuba and Tokyo Univ. of Science Chief of Management Secretariat 2018-04 -- 2019-03 The 7th Retreat of Univ. of Tsukuba and Tokyo Univ. of Science Program committee member 2019-04 -- (current) The Japanese Society for Immunology Councilor 2017-04 -- 2018-03 The 6th Retreat of Univ. of Tsukuba and Tokyo Univ. of Science Management Secretariat 2017-04 -- 2018-03 The Japanese Society for Immunology Cooperation Committee Member - University Management
2020 -- (current) 生存ダイナミクス研究センター 内部交流会TARA Biweekly Mixerオーガナイザー 2018 -- (current) 生存ダイナミクス研究センター 広報委員 - Other activities
2022-07 -- 2022-07 TARA公開講座 令和4年度公開講座「感染と恒常性の生命科学」 “ナチュラルキラー細胞による生体防御” 2022-07 -- 2022-07 筑波大学 高大連携事業 免疫学「感染症」 2018-07 -- 2018-07 TARA公開講座 平成30年度高校生公開講座「生物の生存戦略を科学する」 “ナチュラルキラー細胞による生体防御” 2017-08 -- 2017-08 Menneki Fushigi Mirai 2017 (organized by Kenji Ishiwata, the Japanese Society for Immunology) at Tokyo, Japan. 2008-05 -- 2008-05 Menneki Hushigi Mirai 2008 (organized by Masayuki Miyasaka, the Japanese Society for Immunology) at Tokyo, Japan 2008-04 -- 2008-04 Menneki Town Meeting Tsukuba (organized by Akira Shibuya, the Japanese Society for Immunology) at Ibaraki, Japan.
(Last updated: 2023-09-11)