Kimura Kenichi
- Affiliation
- Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
- Official title
- Assistant Professor
- ORCID
- 0000-0002-0363-8865
- URL
- ;00.2:7&HUZ&9HUZ9&7&Q98:0:'&Q&(Q/5
- Phone
- 029-853-7323
- Research fields
Cell biology Pathological medical chemistry - Research projects
内在性間葉系幹細胞を用いた変形性関節症治療のための再生医療基盤の開発 2023-07 -- 2026-03 木村健一 AMED/「再生・細胞医療・遺伝子治療実現加速化プログラム(再生・細胞医療・遺伝子治療研究開発課題(基礎応用研究課題))」 39,000,000Yen 変形関節症における軟骨変性メカニズムの解明 2023-07 -- 2028-03 木村健一 Takeda Science Foundation/2023年度 医学系研究助成(基礎) 2,000,000Yen CD73陽性細胞による骨髄造血微小環境形成メカニズムの解明 2023-04 -- 2025-03 木村健一 稲盛財団/稲盛研究助成 1,000,000Yen 細胞外マトリクスを基軸とした胸部大動脈疾患の発生機序の解明と新規治療法の開発 2023-04 -- 2027-03 柳沢裕美 日本学術振興会/科学研究費補助金 基盤研究(A) 46,800,000Yen 細胞系譜解析を用いたCD73発現細胞による骨髄ニッチ形成および骨修復機構の解明 2022-04 -- 2025-03 木村健一 日本学術振興会/基盤研究(C) 4,290,000Yen CD73発現細胞による骨髄微小環境の細胞ダイナミクスの解明 2022-04 -- 2023-03 木村健一 ノバルティス科学振興財団/第35回 ノバルティス研究奨励金 1,000,000Yen ミクロフィブリル変異による大動脈解離の病態解明 2021-10 -- 2025-03 柳沢裕美 /国際共同研究加速基金(国際共同研究強化(B)) 19,110,000Yen 微小発現解析による大動脈解離の新規バイオマーカーの探索 2021-11 -- 2023-03 木村健一 かなえ医薬振興財団/2021年度研究助成金 1,000,000Yen 細胞系譜解析から紐解く骨髄微小環境形成機構の解明 2021-01 -- 2022-04 木村健一 上原記念生命科学財団/2020年度 研究奨励金 2,000,000Yen 細胞系譜解析から紐解く骨髄造血微小環境の形成機構の解明 2020-12 -- 2021-12 木村健一 テルモ生命科学振興財団/2020年度 研究助成 2,000,000Yen more... - Career history
2020-04 -- (current) 筑波大学 生存ダイナミクス研究センターAssistant Professor 2012-09 -- 2020-03 University of Bonn, Institute of Physiology IPostdoctoral Reseacher 2012-04 -- 2012-08 筑波大学 医学医療系Postdoctoral Reseacher - Academic background
-- 2012-03 筑波大学大学院人間総合科学研究科 生命システム医学専攻 - Degree
2012-03 博士(医学) 筑波大学 - Academic societies
2021 -- (current) The Molecular Biology Society of Japan 2006 -- (current) 日本再生医療学会 2011 -- (current) 国際幹細胞学会 2021 -- (current) The Japanese Biochemical Society 2021 -- (current) The Japanese Vascular Biology and Medicine Organization 2021 -- (current) THE JAPANESE CIRCULATION SOCIETY 2012 -- 2020 ドイツ生理学会 - Honors & Awards
2022-12 The Excellent Abstract Award 2021-12 日本血管生物医学会 若手奨励賞 2009-11 The Excellent Poster Award 2009-09 The Young Scientist Award - Articles
- Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo
Kimura Kenichi; Breitbach Martin; Schildberg Frank A.; He...
Bone Reports/15, 2021-12 - Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy.
Kenichi Kimura; Astrid Ooms; Kathrin Graf-Riesen; Maithre...
Nature Communications/12(1), 2021-06 - Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels
Kimura Kenichi; Ramirez Karina; Nguyen Tram Anh Vu; Yamas...
Scientific Reports/11, 2021-04 - Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation As Gαq-Protein Ligands
Gütschow Michael; Küppers Jim; Benkel Tobias; Annala ...
Chemistry (Weinheim an der Bergstrasse, Germany), 2020-05 - In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche
Breitbach Martin; Kimura Kenichi; Luis Tiago C.; Fuegeman...
CELL STEM CELL/22(2)/pp.262-+, 2018-02 - Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling
Roell Wilhelm; Klein Alexandra M; Breitbach Martin; Be...
Scientific reports/8(1)/p.7145, 2018-04 - Midbody Positioning and Distance Between Daughter Nuclei Enable Unequivocal Identification of Cardiomyocyte Cell Division in Mice
Hesse Michael; Doengi Michael; Becker Alexandra; Kimur...
Circulation research/123(9)/pp.1039-1052, 2018-04 - PECAM/eGFP transgenic mice for monitoring of angiogenesis in health and disease
Winkler Florian; Herz Katia; Rieck Sarah; Kimura Keni...
Scientific reports/8(1), 2018-04 - Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells.
Vuong Cat Khanh; Kimura Kenichi; Kato Toshiki; Sato Kazu...
Stem Cells and Development, 2018-01 - Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity
Nhu Thuy Trinh; Toshiharu Yamashita; Kinuko Ohneda; Kenic...
Stem Cells and Development/25(10)/pp.760-773, 2016-03 - A chemokine receptor, CXCR4, which is regulated by hypoxia inducible factor 2α, iscrucial for functional EPC migration to ischemic tissue and wound repair.
Tu Tran Cam; Nagano Masumi; Yamashita Toshiharu; Hamada ...
Stem Cells Dev./25/pp.266-276, 2016-02 - Impaired Expression of HIF-2 alpha Induces Compensatory Expression of HIF-1 alpha for the Recovery From Anemia
Tsuboi Ikki; Yamashita Toshiharu; Nagano Masumi; Kimura ...
JOURNAL OF CELLULAR PHYSIOLOGY/230(7)/pp.1534-1548, 2015-07 - Hypoxia-inducible factor-3 alpha promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene
Kobayashi Satomi; Yamashita Toshiharu; Ohneda Kinuko; Nag...
GENES TO CELLS/20(3)/pp.224-241, 2015-03 - Dual Functions of Hypoxia-Inducible Factor 1 Alpha for the Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage
Zhao Yang; Takasaki Mami; Tsuboi Ikki; Kimura Kenichi; Sa...
Stem Cells Dev., 2014 - The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions.
Kimura Kenichi; Nagano M; Salazar G; 山下 年晴; Tsuboi I; Mis...
STEM CELLS AND DEVELOPMENT/23(5)/pp.488-501, 2014-03 - Functional endothelial progenitor cells selectively recruit neurovascular protective monocyte-derived F4/80+/Ly6c+ macrophages in a mouse model of retinal degeneration
Shinichi Fukuda; Nagano Masumi; Toshiharu Yamashita; Kimu...
Stem Cells/31(10)/pp.2149-2161, 2013-10 - Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal ste cells promote, glioblastoma multiforme proliferation
Keiko Akimoto; Kenichi Kimura; 長野 真澄; Shingo Takano; Geor...
Stem Cell and Development/22(9)/pp.1370-1386, 2013-05 - Identification of Human Placenta-Derived Mesenchymal Stem Cells Involved in Re-Endothelialization
Tran Tu Cam; Kimura Kenichi; Nagano Masumi; Yamashita To...
JOURNAL OF CELLULAR PHYSIOLOGY/226(1)/pp.224-235, 2011-01 - Hypoxia Responsive Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood Are Effective for Bone Repair
Nagano Masumi; Kimura Kenichi; Yamashita Toshiharu; Ohned...
STEM CELLS AND DEVELOPMENT/19(8)/pp.1195-1210, 2010-08 - Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood
Nagano Masumi; Yamashita Toshiharu; Hamada Hiromi; Ohneda...
BLOOD/110(1)/pp.151-160, 2007-07
- Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo
- Books
- 大動脈瘤への分子生物学的アプローチ
木村 健一; 柳沢裕美
心臓/日本医学出版, 2022-06
- 大動脈瘤への分子生物学的アプローチ
- Conference, etc.
- 新規Fibrillin-1点変異マウスモデルを用いた大動脈解離発症機序の解明
本山絵理; 木村 健一; 石井 柳太郎; 神吉 佐智子; 中邨 智之; 柳沢 裕美
第55回日本結合組織学会/2023-06-24 - Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy due to sarcomere disruption and protein aggregate formation
木村 健一
第20回幹細胞シンポジウム若手の会/2023-05-19 - Bone marrow CD73+ mesenchymal stem cells display increased stemness and promote fracture healing
木村 健一
第20回幹細胞シンポジウム/2023-05-19--2023-05-20 - A Novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene
Kimura Kenichi; Motoyama Eri; Ishii Ryutaro; Yamashiro Y...
The 6th JCS Council Forum on Basic CardioVascular Research/2022-12-16--2022-12-17 - Fate mapping analysis of developmental mechanism in bone marrow niche
木村 健一; 石井 柳太郎; 渡辺 純菜; Bernd Fleischmann; 柳沢 裕美
第45回日本分子生物学会年会/2022-11-30--2022-12-02 - Dynamics of CD73 during retinal development
石井 柳太郎; 木村健一; 柳沢裕美
第45回日本分子生物学会年会/2022-11-30--2022-12-02 - A Novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene
Kimura Kenichi; Motoyama Eri; Ishii Ryutaro; Sugiyama ...
11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions/2022-08-29--2022-09-01 - Dynamics of CD73 during retinal development
石井 柳太郎; 木村健一; 柳沢裕美
第8回 MatriCell フォーラム/2022-09-10--2022-09-11 - 新規Fbn1 遺伝子変異マウスを用いた大動脈解離発症機序の解明
木村 健一
第7回血管生物医学会若手研究会/2022/03/04--2022/03/05 - Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy
Kimura Kenichi
CVMW 2021/2021-12-10--2021-12-11 - Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy
Kimura Kenichi
第5回日本循環器学会基礎研究フォーラム/2021-09-11--2021-09-12 - Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy due to sarcomere disruption and protein aggregate formation
木村 健一
第94回日本生化学会大会/2021-11-03--2021-11-05 - 新規Fbn1 遺伝子変異マウスを用いたマルファン症候群の大動脈解離発症機序の解明
本山絵理; 木村健一; 石井柳太郎; 杉山夏緒里; 山城義人; 神吉佐智子; 柳沢 裕美
エラスチン・関連分子研究会学術集会/2021-12-18--2021-12-19 - 細胞系譜解析を用いた角結膜幹細胞の動態解明
石井 柳太郎; 木村 健一; 柳沢 裕美; 佐田 亜衣子
第16回和歌山TRP研究会/2021-11-22 - Contribution of PDGFRα-positive cell populations during vascular remodeling
Ramirez Karina; Kimura Kenichi; An Nguyen Vu Tram; Yamash...
TGSW2020/2020-09-28--2020-09-30 - 細胞系譜解析モデルを用いた骨髄微小環境形成メカニズムの解明
木村 健一; 石井 柳太郎; Bernd K. Fleischmann; 柳沢 裕美
第20回日本再生医療学会総会/2021-03 - Myopathy causing BAG3P209L protein leads to restrictive cardiomyopathy caused by aggregate formation and sarcomere disruption in cardiomyocytes
Graf-Riesen K; Kimura Kenichi; Unger A; Lother A; Hein L...
BCVS scientific sessions/2019-07 - Mechanical stress-induced pathomechanisms in BAG3-associated myopathies.
Kimura Kenichi; K Graf-Riesen; BK Fleischmann; M Hesse
Annual Meeting of the Research Unit FOR 2743/2019-09 - BirA* Mouse Lines for the Analysis of Cell Type-Specific Proteomes in vivo.
S Ahmadi; E Pourbarkhordariesfandabadi; Kimura Kenichi; A...
The 53rd annual meeting of the German Society for Mass Spectrometry (DGMS) including 27th ICP-MS User’s Meeting/2020-03 - First Draft of the In Vivo Beta Cell Proteome by Cell Type Specific Proximity Biotinylation in BirA* Mice
S Ahmadi; E Pourbarkhordariesfandabadi; A Egert; M Breit...
The 68th American Society for Mass Spectrometry/2020-06 - Contribution of PDGFRa-positive cell population during vascular remodeling
Ramirez Karina; Kimura Kenichi; Nguyen Tram Anh Vu; Yamas...
Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
- 新規Fibrillin-1点変異マウスモデルを用いた大動脈解離発症機序の解明
- Teaching
2023-10 -- 2023-12 Topics in Vascular Biology University of Tsukuba. 2023-10 -- 2024-02 Medical Science Seminar V: Career Path University of Tsukuba. 2023-04 -- 2023-08 Medical Science Seminar V: Career Path University of Tsukuba. 2023-10 -- 2024-02 Seminar in Human Medical Biology II University of Tsukuba. 2023-10 -- 2023-12 Oncology University of Tsukuba. 2023-04 -- 2023-08 Practice in Human Medical Biology I University of Tsukuba. 2023-04 -- 2023-08 Seminar in Human Medical Biology I University of Tsukuba. 2023-10 -- 2024-02 Special Practice in Human Biology I University of Tsukuba. 2023-10 -- 2024-02 Practice in Human Medical Biology II University of Tsukuba. 2023-04 -- 2023-08 Lecture and Discussion in Human Medical Biology I University of Tsukuba. more... - University Management
2021-04 -- (current) フロンティア医科学専攻キャリア支援担当委員会 委員
(Last updated: 2023-07-17)