Kaushik Mahesh Kumar(カウシック マヘシュ クマール)
- 所属
- 筑波大学
- 職名
- 助教
- ORCID
- 0000-0003-4286-1573
- 性別
- 男性
- 学外所属
The University of Tsukuba International Institute for Integrative Sleep Medicine Assistant Professor - 研究キーワード
Neurobiology of sleep-wakefulness CNS Disorders Narcolepsy/Cataplexy Seizure/Epilepsy Pre-clinical studies - 研究課題
Investigating the effects of orexin antagonists on sleep disorder narcolepsy and underlying molecular and cellular changes in brain architecture 2014-09 -- 2020-12 / Evaluation of the wake-inducing activity of novel compounds by Sumitomo Dainippon Pharma in murine models 2018-01 -- 2019-01 Sumitomo Dainipponn Pharma, Japan/ 5,000,000円 Development of therapy for the treatment of cataplexy/narcolepsy by intrathecal orexin administration 2014-12 -- 2018-08 / Evaluation of novel compounds by MTPC for their wake-inducing potential and narcolepsy inhibiting activity in murine models. 2017-01 -- 2018-01 Mitsubishi Tanabe Pharma Co. (MTPC), Japan/ 10,000,000円 Role of Prostaglandin D2 in epileptic seizures and post-ictal pathological sleep regulation 2011-01 -- 2018-01 / b. Identification and estimation of stress mitigating and sleep restoring potential of octacosanol 2014-01 -- 2017-01 / Identification and evaluation of somnogenic components of Ashwagandha (Withania somnifera) 2014-01 -- 2017-01 / - 職歴
2021-08 -- (現在) 筑波大学国際統合睡眠医科学研究機構Assistant Professor 2014-09 -- 2021-07 International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, JapanMolecular Genetics of Sleep (Yanagisawa Lab).Researcher 2014-04 -- 2014-08 Indiana University of School of Medicine, South Bend, IN, USADepartment of Toxicology and Pharmacology.Postdoctoral Fellow 2013-03 -- 2013-12 International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, JapanResearcher 2011-03 -- 2013-02 Osaka Bioscience Institute (OBI), Osaka, JapanDepartment of Molecular Sleep (2nd Department).Postdoctoral Fellow - 学歴
2005-02 -- 2010-12 All India Institute of Medical Sciences (AIIMS), New Delhi, India. Department of Physiology. Ph.D. 2002-07 -- 2004-06 Jiwaji University, Gwalior, Madhya pradesh, India School of Studies in Neuroscience. M.Sc. 1998-07 -- 2001-06 Maharashi Dayananda University, Rohtak, Haryana Pt. Jawahar Lal Nahru College, Faridabad. B.Sc. - 取得学位
2001-06 B.Sc. Maharishi Dayananda University 2004-06 M.Sc. (Master's in Neuroscience) School of Studies in Neurosciences, Jiwaji University 2010-12 Ph.D. All India Institute of Medical Sciences (AIIMS), New Delhi - 所属学協会
-- (現在) Japanese Society for Sleep Research (JSSR) -- (現在) Indian Society for Sleep Research (ISSR) -- (現在) Association of Physiologists and Pharmacologist of India -- (現在) Indian Academy of Neuroscience - 受賞
2011-03 Takeda Science Foundation Award for Research In Japan Postdoctoral fellowship, Osaka Bioscience Institute (OBI), Osaka, Japan 2010-12 4th conference of Indian Society for Sleep Research (ISSR), Trivandrum, India Best Paper Award, ISSR Conference 2009-12 Travel Award ISN/APSN/IBRO/SNCI advance school on neurodegenerative diseases, Cochin, India 2008-07 Travel Award Swiss Society for Neuroscience 2007-08 Joint Travel Award WFSRS, Sleep Conference, Cairn, Australia 2009-10 Travel Award 6th Asian Sleep Research Society (ASRS) Conference, Osaka, Japan 2008-06 Travel Award ISN/APSN/IBRO school, Fudan University, Shanghai, China - 論文
- Face validation and pharmacologic analysis of Sik3Sleepy mutant mouse as a possible model of idiopathic hypersomnia
Elhosainy Asmaa; Suzuki-Abe Haruka; Kaushik Mahesh K; ...
European journal of pharmacology/954, 2023-09-05 - Face validation and pharmacologic analysis of Sik3Sleepy mutant mouse as a possible model of idiopathic hypersomnia
Elhosainy Asmaa; Suzuki-Abe Haruka; Kaushik Mahesh K; Kim...
European journal of pharmacology/954, 2023-09-05 - Face validation and pharmacologic analysis of Sik3Sleepy mutant mouse as a possible model of idiopathic hypersomnia
Elhosainy Asmaa; Suzuki-Abe Haruka; Kaushik Mahesh K; ...
EUROPEAN JOURNAL OF PHARMACOLOGY/954, 2023-09-05 - Glutamate microinjection at the medial preoptic area enhances slow wave sleep in rats
Kaushik Mahesh K; Kumar Velayudhan Mohan; Mallick Hrud...
Behavioural brain research/217(1)/pp.240-243, 2011-02-02 - Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex
Cheriyan John; Kaushik Mahesh K; Ferreira Ashley N; Sh...
eNeuro/3(2), 2016-03 - Acute Social Defeat Stress Increases Sleep in Mice
Fujii Shinya; Kaushik Mahesh K; Zhou Xuzhao; Korkutata M...
Frontiers in neuroscience/13/p.322, 2019-04 - The Leptomeninges Produce Prostaglandin D-2 Involved in Sleep Regulation in Mice
Cherasse Yoan; Aritake Kosuke; Oishi Yo; Kaushik Mahesh ...
FRONTIERS IN CELLULAR NEUROSCIENCE/12, 2018-10 - Induction of narcolepsy-like symptoms by orexin receptor antagonists in mice
Kaushik Mahesh K; Aritake Kosuke; Cherasse Yoan; Imani...
Sleep/44(8), 2021-02 - Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism
R Sharma; T Matsuzaka; MK Kaushik; T Sugasawa; H Ohno; Y ...
Scientific Reports/9(1)/p.5169, 2019-03 - Continuous intrathecal orexin delivery inhibits cataplexy in a murine model of narcolepsy
Kaushik Mahesh K; Aritake Kosuke; Imanishi Aya; Kanbayash...
Proceedings of the National Academy of Sciences of the United States of America/115(23)/pp.6046-6051, 2018-05 - Octacosanol restores stress-affected sleep in mice by alleviating stress
Kaushik Mahesh K; Aritake Kosuke; Takeuchi Atsuko; Yanagi...
Scientific reports/7(1)/p.8892, 2017-08 - Natural (∆(9)-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor
Malyshevskaya Olga; Aritake Kosuke; Kaushik Mahesh K; ...
Scientific reports/7, 2017-09 - Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction
Kaushik Mahesh K.; Kaul Sunil C.; Wadhwa Renu; Yanagisawa...
PLOS ONE/12(2), 2017-02 - Prostaglandin D-2 is crucial for seizure suppression and postictal sleep
Kaushik Mahesh K.; Aritake Kosuke; Kamauchi Shinya; Hayai...
EXPERIMENTAL NEUROLOGY/253/pp.82-90, 2014-03 - Substrate-induced product-release mechanism of lipocalin-type prostaglandin D synthase
Shimamoto Shigeru; Nakagawa Yusuke; Hidaka Yuji; Maruno ...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/569/pp.66-71, 2021-09 - A gain-of-function study of amelioration of pentylenetetrazole-induced seizures by endogenous prostaglandin D
Kaushik Mahesh K; Aritake Kosuke; Cherasse Yoan; Sharm...
Neuroscience letters/686/pp.140-144, 2018-09 - Effect of Lateral Preoptic Area Lesion on Sleep Wakefulness and Thermoregulation In Cold Acclimatized Rats
Kaushik M.K; Mallick H.N; Kumar V.M
Indian J Physiol Pharmacol./59(3)/pp.275-284, 2015-01 - Hypothalamic temperature: a key regulator in homeostatic restoration of sleep during chronic cold exposure in rats.
MK Kaushik; VM Kumar; HN Mallick
Indian J Physiol Pharmacol./56(4)/pp.301-313, 2012-10 - Glutamate microinjection in the medial septum of rats decreases paradoxical sleep and increases slow wave sleep
Didhiti Mukherjee Mahesh K. Kaushik Ashok Kumar Jaryal ...
NeuroReport/23(7)/pp.451-456, 2012-05 - Changes in Hypothalamic and Body Temperatures During 24 Hours in Rats
Kaushik Mahesh Kumar
Indian Journal of Physiology and Pharmacology/53(1)/pp.88-92, 2009-01
- Face validation and pharmacologic analysis of Sik3Sleepy mutant mouse as a possible model of idiopathic hypersomnia
- 会議発表等
- Glutamate at medial preoptic area increases sleep
K. Kaushik Mahesh
Indian Society for Sleep Research conference, Bangalore, India/2007-07-01 - Alteration in brain temperature, body temperature and sleep wakefulness during chronic cold exposure in rats
Mahesh K. Kaushik
Silver Jubilee Conference of Indian Academy of Neuroscience/2007-11-01 - Changes in sleep-wakefulness after injection of glutamate at medial preoptic area
Kaushik MK; Kumar VM; Mallick HN
Asia Pacific Society of Neurochemistry Conference, Shanghai, China./2008-06-01 - Glutamate at medial preoptic area increases sleep: A pilot study
Kaushik MK; Kumar VM; Mallick HN
FENS Forum of European Neuroscience, (12-16, 2008) Geneva, Switzerland/2008-08-01 - Effect of lateral preoptic area lesion on sleep, hypothalamic and body temperature in rats
Kaushik MK; Kumar VM; Mallick HN
6th Asia Sleep Research Society (ASRS) Conference, Osaka, Japan/2009-10-24--2009-10-27 - Effect of the lateral preoptic area lesion on sleep-wakefulness, hypothalamic and body temperature during chronic cold exposure
K. Kaushik Mahesh
??/2010-12-13 - The role of Prostaglandin D2 in causing post-ictal sleep following seizures
K. Kaushik Mahesh
WorldSleep2011, Wold Federation of Sleep Research and Sleep Medicine Societies, Kyoto, Japan/2011-10-01 - The role of prostaglandin D2 in causing post-ictal sleep following seizures
Mahesh K. Kaushik
Indian Academy of neuroscience (IAN), Conference, DIPAS, New Delhi, India./2011-11-01 - The role of prostaglandin D2 in seizures and post-ictal sleep
MK Kaushik; M Lazarus; K Aritake; S Kamauchi; Y Cherasse...
Japanese Society for Sleep Research (JSSR) Annual Conference, (27-30 June, 2012) Yokohama, Japan/2012-06-01 - The role of prostaglandin D2 in seizures and post-ictal sleep
K. Kaushik Mahesh
7th Asian Sleep Research Society (ASRS) conference, (Nov-Dec, 2012) Taipei, Taiwan./2012-11--2012-12 - Prostaglandin D2: role in seizure suppression and postictal sleep
Kaushik Mahesh Kumar
5th DAILAB Café, AIST, Tsukuba, Japan/2014-11-17 - Prostaglandin D2 is crucial for seizure suppression and postictal sleep
Mahesh K. Kaushik
Indian Scientists Association in Japan (ISAJ)” symposium, Tokyo, Japan/2014-12-01 - Identification of somnogenic component of Ashwagandha (Withania somnifera) leaf
Kaushik MK; Sunil C. Kaul; Renu Wadhwa; Urade Y
6th World Congress on Sleep Medicine (WASM), Seoul, Korea/2015-03-21--2015-03-25 - Somnogenic component of Ashwagandha: an alternative insomnia therapy
K. Kaushik Mahesh
Indian Academy of neuroscience (IAN), Conference, NBRC, Manesar, Haryana, India/2016-10-19--2016-10-21 - Chronic orexin antagonist suvorexant administration induces sleep and cataplexy in mice
K. Kaushik Mahesh
Silver Jubilee Conference of Indian Society for Sleep Research (ISSR), (22-23 Sep, 2017), Goa, India/2017-09-22--2017-09-23 - Why do need to sleep? The biggest mystery of neuroscience
Mahesh K. Kaushik
DAICENTER DAILAB PIKNIKH Series XXVII, AIST, Tsukuba, Japan (Oct 17, 2018)/2018-10-17 - Sleep need and its relation to neurological disorders
Mahesh K. Kaushik
Indian Scientists Association in Japan (ISAJ)” symposium, AIST, Tsukuba, Japan/2018-12-07 - Sleep and Narcolepsy- mysteries, mechanisms and manipulations
Mahesh K. Kaushik
PIKHNIKH, DAILAB, workshop, AIST, Tsukuba, Japan/2019-01-21 - Chronic orexin receptor blockage induces Narcoleptic behavior by reducing orexin peptide synthesis in mice
K. Kaushik Mahesh; Aritake Kosuke; Kakizaki Miyo; Kanb...
WorldSleep 2019, Vancouver, Canada./2019-09-22--2019-09-25 - Solving the mysteries of sleep: The role of the orexinergic system in sleep and narcolepsy
Mahesh K. Kaushik
PIKHNIKH, DAILAB, workshop, AIST, Tsukuba, Japan. (October 08, 2019)/2019-10-08
- Glutamate at medial preoptic area increases sleep
- 一般講演
- Novel therapy for narcolepsy by intrathecal orexin slow infusion in the murine model
Mahesh K. Kaushik
Department of Physiology, All India Institute of Medical Sciences, New Delhi, India/2016-03-04 - Prostaglandin D2 (PGD2) in sleep and seizures
K. Kaushik Mahesh
Department of Physiology, All India Institute of Medical Sciences, New Delhi/2016-10-17 - Role of Prostaglandin D2 (PGD2) in sleep and seizures
Mahesh K. Kaushik
SOS Neuroscience, Jiwaji University, Gwalior, Indi/2016-10-25 - Orexin antagonist in sleep promotion: problems and warning
K. Kaushik Mahesh
Organized by Akita University, sponsored by Eisai Pharma, Japan (Feb 01, 2017)/2017-02-01 - Orexin and its antagonist in sleep and narcolepsy
Mahesh K. Kaushik
All India Institute of Medical Sciences (AIIMS), Jodhpur, India (Sep 25, 2017)/2017-09-25 - Development of treatment for narcolepsy by continues intrathecal orexin administration
Mahesh K. Kaushik
Department of Physiology, All India Institute of Medical Sciences (AIIMS), New Delhi/2018-10-27 - Orexin and orexin receptors in sleep/wake regulation and narcolepsy
Mahesh K. Kaushik
SRI International, Menlo Park, CA, USA./2020-02-07 - Solving the mysteries of sleep
Mahesh K. Kaushik
International Webinar series-1, Integrated Association of Medical, Basic and Social Scientists (IAMBSS)/2020-08-27 - Role of orexins/hypocretins in sleep/wake regulation and narcolepsy
Mahesh K. Kaushik
DAILAB, CAFE, AIST, Tsukuba, Japan/2021-01-14
- Novel therapy for narcolepsy by intrathecal orexin slow infusion in the murine model
(最終更新日: 2023-04-11)